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- W1974949649 abstract "We report that, in peripheral blood T cells, the V beta 8 gene product is much more represented on CD4+CD8- than on CD4-CD8+ lymphocytes. This skewing was observed in all individuals tested and with two independent strategies, one of which allows the selection of V beta 8+ T cells independently from their major histocompatibility complex-antigen specificity. Our data imply that the human V beta 8 gene product confers class II restriction specificity and that both the T cell receptor chains and CD4 molecule are involved in the selection of the T cell repertoire." @default.
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- W1974949649 date "1990-12-01" @default.
- W1974949649 modified "2023-09-23" @default.
- W1974949649 title "Expression of the human Vβ8 gene product preferentially correlates with class II major histocompatibility complex restriction specificity" @default.
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- W1974949649 doi "https://doi.org/10.1002/eji.1830201244" @default.
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