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- W1975011608 abstract "Ribonucleic acid extracted from four stages during the developmental cycle of the cellular slime mold Dictyostelium discoideum was hybridized with purified single-copy nuclear DNA. The hybrids formed were shown to have the high thermal stability indicative of single-copy DNA/RNA hybrids and the DNA extracted from them reassociates with single-copy DNA. The hybridization studies indicate that there are, during development, qualitative and quantitative changes in the portion of the single-copy portion of the genome transcribed. Over-all, 56% of the genome (approximately 16 to 17 × 106 nucleotide pairs) are represented by transcripts between the amoeba and midculmination stages. Some 18 to 20% of the genome consist of sequences which are represented at all stages while approximately 36 to 38% of the genome consist of sequences which are represented only at particular developmental stages. The possible uncertainties of these numbers are discussed." @default.
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- W1975011608 date "1972-05-01" @default.
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- W1975011608 title "Changes in the expression of single-copy DNA during development of the cellular slime mold Dictyostelium discoideum" @default.
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- W1975011608 doi "https://doi.org/10.1016/0022-2836(72)90420-2" @default.
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