Matches in SemOpenAlex for { <https://semopenalex.org/work/W1975012397> ?p ?o ?g. }
- W1975012397 endingPage "1282" @default.
- W1975012397 startingPage "1271" @default.
- W1975012397 abstract "We used energy minimization of a molecular mechanical force field to evaluate spermine interactions with B-form DNA oligomers with either alternating purine/pyrimidine or homopolymeric sequences. Four different positions for spermine docking—within, along, and bridging the minor groove and bridging the major groove—were assessed for each sequence. Interaction at the major groove of alternating purine/pyrimidine sequences appears to be the most favorable of all models assessed, and are associated with significant bending of DNA. Interactions at the major groove of homopolymers were less favorable than those of heteropolymers and showed little or no bending. Interactions with the minor groove were most favorable for spermine positioned near the base of the groove, and became less favorable as spermine was moved toward the top of the groove. Association along the phosphate backbone alone was the least favorable of the interactions." @default.
- W1975012397 created "2016-06-24" @default.
- W1975012397 creator A5008338823 @default.
- W1975012397 creator A5030097391 @default.
- W1975012397 creator A5066206589 @default.
- W1975012397 date "1990-01-01" @default.
- W1975012397 modified "2023-10-18" @default.
- W1975012397 title "Molecular mechanics of the interactions of spermine with DNA: DNA bending as a result of ligand binding" @default.
- W1975012397 cites W1491581051 @default.
- W1975012397 cites W1518002808 @default.
- W1975012397 cites W1526944695 @default.
- W1975012397 cites W1532829068 @default.
- W1975012397 cites W1533307088 @default.
- W1975012397 cites W1783564941 @default.
- W1975012397 cites W1963805722 @default.
- W1975012397 cites W1969469290 @default.
- W1975012397 cites W1969776708 @default.
- W1975012397 cites W1979204453 @default.
- W1975012397 cites W1990933742 @default.
- W1975012397 cites W1993753287 @default.
- W1975012397 cites W1996852546 @default.
- W1975012397 cites W2012719938 @default.
- W1975012397 cites W2012750519 @default.
- W1975012397 cites W2020196912 @default.
- W1975012397 cites W2031425422 @default.
- W1975012397 cites W2041550899 @default.
- W1975012397 cites W2050560798 @default.
- W1975012397 cites W2051883709 @default.
- W1975012397 cites W2052948676 @default.
- W1975012397 cites W2053427405 @default.
- W1975012397 cites W2056144602 @default.
- W1975012397 cites W2058163213 @default.
- W1975012397 cites W2065367918 @default.
- W1975012397 cites W2084320116 @default.
- W1975012397 cites W2094249347 @default.
- W1975012397 cites W2105363183 @default.
- W1975012397 cites W2107701857 @default.
- W1975012397 cites W2156236585 @default.
- W1975012397 cites W2160616001 @default.
- W1975012397 cites W2180006187 @default.
- W1975012397 cites W4238270754 @default.
- W1975012397 doi "https://doi.org/10.1093/nar/18.5.1271" @default.
- W1975012397 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/330444" @default.
- W1975012397 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2320418" @default.
- W1975012397 hasPublicationYear "1990" @default.
- W1975012397 type Work @default.
- W1975012397 sameAs 1975012397 @default.
- W1975012397 citedByCount "158" @default.
- W1975012397 countsByYear W19750123972012 @default.
- W1975012397 countsByYear W19750123972013 @default.
- W1975012397 countsByYear W19750123972014 @default.
- W1975012397 countsByYear W19750123972015 @default.
- W1975012397 countsByYear W19750123972016 @default.
- W1975012397 countsByYear W19750123972017 @default.
- W1975012397 countsByYear W19750123972018 @default.
- W1975012397 countsByYear W19750123972019 @default.
- W1975012397 countsByYear W19750123972020 @default.
- W1975012397 countsByYear W19750123972021 @default.
- W1975012397 countsByYear W19750123972022 @default.
- W1975012397 countsByYear W19750123972023 @default.
- W1975012397 crossrefType "journal-article" @default.
- W1975012397 hasAuthorship W1975012397A5008338823 @default.
- W1975012397 hasAuthorship W1975012397A5030097391 @default.
- W1975012397 hasAuthorship W1975012397A5066206589 @default.
- W1975012397 hasBestOaLocation W19750123972 @default.
- W1975012397 hasConcept C12554922 @default.
- W1975012397 hasConcept C181199279 @default.
- W1975012397 hasConcept C185581394 @default.
- W1975012397 hasConcept C185592680 @default.
- W1975012397 hasConcept C191897082 @default.
- W1975012397 hasConcept C192562407 @default.
- W1975012397 hasConcept C2776109719 @default.
- W1975012397 hasConcept C2779321679 @default.
- W1975012397 hasConcept C2779472054 @default.
- W1975012397 hasConcept C3019303373 @default.
- W1975012397 hasConcept C552990157 @default.
- W1975012397 hasConcept C55493867 @default.
- W1975012397 hasConcept C71240020 @default.
- W1975012397 hasConcept C8010536 @default.
- W1975012397 hasConcept C86803240 @default.
- W1975012397 hasConceptScore W1975012397C12554922 @default.
- W1975012397 hasConceptScore W1975012397C181199279 @default.
- W1975012397 hasConceptScore W1975012397C185581394 @default.
- W1975012397 hasConceptScore W1975012397C185592680 @default.
- W1975012397 hasConceptScore W1975012397C191897082 @default.
- W1975012397 hasConceptScore W1975012397C192562407 @default.
- W1975012397 hasConceptScore W1975012397C2776109719 @default.
- W1975012397 hasConceptScore W1975012397C2779321679 @default.
- W1975012397 hasConceptScore W1975012397C2779472054 @default.
- W1975012397 hasConceptScore W1975012397C3019303373 @default.
- W1975012397 hasConceptScore W1975012397C552990157 @default.
- W1975012397 hasConceptScore W1975012397C55493867 @default.
- W1975012397 hasConceptScore W1975012397C71240020 @default.
- W1975012397 hasConceptScore W1975012397C8010536 @default.
- W1975012397 hasConceptScore W1975012397C86803240 @default.
- W1975012397 hasIssue "5" @default.
- W1975012397 hasLocation W19750123971 @default.
- W1975012397 hasLocation W19750123972 @default.