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- W1975030611 abstract "The effect of daily injections of 0.1 mg/kg reserpine (Serpasil) on pathologic calcification of cardiac tissue in 12- to 16-month-old DBA strain mice was studied. After 3 weeks of daily injections, the tissue calcium levels were decreased significantly from control levels of 18.6 (atrial) to 13.2 and 20.1 (ventricular) to 12.8 meq Ca ++ /kg fat-free dry weight respectively. Histological observations also showed a decrease in spontaneous calcification of cardiac tissue in the reserpinized mice. Frequent findings in the calcified areas of the reserpine-treated mice were: less extensive calcification, a more granular appearance of the mineral, an associated inflammatory reaction, and adjacent areas of myocardial necrosis." @default.
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- W1975030611 date "1969-06-01" @default.
- W1975030611 modified "2023-09-25" @default.
- W1975030611 title "Effects of reserpine on cardiac calcification in DBA mice" @default.
- W1975030611 doi "https://doi.org/10.1139/y69-093" @default.
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