Matches in SemOpenAlex for { <https://semopenalex.org/work/W1975064555> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W1975064555 endingPage "382" @default.
- W1975064555 startingPage "379" @default.
- W1975064555 abstract "Purpose of review A wide distribution of the eye's muscarinic receptor system has been found and several roles for the muscarinic system in the eye proposed, although functional consequences of muscarinic receptor activation are not always fully characterized. The present paper reviews current knowledge about the presence of muscarinic receptors in the ocular surface and the implication of alterations on their expression and/or functioning in eye diseases. Recent findings Several authors have described alterations in muscarinic receptor subtype expression in the eye under pathological conditions. In conjunctiva of vernal keratoconjunctivitis patients, the expression of muscarinic receptor subtypes is altered in both the epithelium and stroma. Under proinflammatory conditions, M2-muscarinic receptor expression is upregulated in conjunctival epithelial cells in vitro. M3-muscarinic receptor altered distribution has been found in the lacrimal gland of NOD mice. Summary The cholinergic muscarinic system plays diverse roles. Alteration in the expression and/or functioning of muscarinic receptors may be implicated in the etiopathogenesis of some ocular diseases. Their pharmacological regulation may therefore have therapeutic value. Knowledge of the specific receptor subtypes expressed in each tissue may help to avoid some undesired secondary side effects in some cases when muscarinic agonists or antagonists are used." @default.
- W1975064555 created "2016-06-24" @default.
- W1975064555 creator A5000593371 @default.
- W1975064555 creator A5087265635 @default.
- W1975064555 date "2006-10-01" @default.
- W1975064555 modified "2023-10-18" @default.
- W1975064555 title "Muscarinic receptors in the ocular surface" @default.
- W1975064555 cites W166419991 @default.
- W1975064555 cites W1989094823 @default.
- W1975064555 cites W1997391627 @default.
- W1975064555 cites W2008090567 @default.
- W1975064555 cites W2010092017 @default.
- W1975064555 cites W2024921065 @default.
- W1975064555 cites W2030561998 @default.
- W1975064555 cites W2033476232 @default.
- W1975064555 cites W2038044751 @default.
- W1975064555 cites W2042294748 @default.
- W1975064555 cites W2050443860 @default.
- W1975064555 cites W2062540706 @default.
- W1975064555 cites W2096941312 @default.
- W1975064555 cites W2099756346 @default.
- W1975064555 cites W2104395061 @default.
- W1975064555 cites W2143112599 @default.
- W1975064555 cites W2146310002 @default.
- W1975064555 cites W2160767885 @default.
- W1975064555 cites W2263274011 @default.
- W1975064555 cites W2883249851 @default.
- W1975064555 cites W6152212 @default.
- W1975064555 doi "https://doi.org/10.1097/01.all.0000244800.71851.0c" @default.
- W1975064555 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16954793" @default.
- W1975064555 hasPublicationYear "2006" @default.
- W1975064555 type Work @default.
- W1975064555 sameAs 1975064555 @default.
- W1975064555 citedByCount "6" @default.
- W1975064555 countsByYear W19750645552013 @default.
- W1975064555 countsByYear W19750645552014 @default.
- W1975064555 countsByYear W19750645552021 @default.
- W1975064555 crossrefType "journal-article" @default.
- W1975064555 hasAuthorship W1975064555A5000593371 @default.
- W1975064555 hasAuthorship W1975064555A5087265635 @default.
- W1975064555 hasConcept C116289061 @default.
- W1975064555 hasConcept C126322002 @default.
- W1975064555 hasConcept C134018914 @default.
- W1975064555 hasConcept C170493617 @default.
- W1975064555 hasConcept C207723603 @default.
- W1975064555 hasConcept C33789571 @default.
- W1975064555 hasConcept C47488739 @default.
- W1975064555 hasConcept C64123433 @default.
- W1975064555 hasConcept C64615621 @default.
- W1975064555 hasConcept C71924100 @default.
- W1975064555 hasConceptScore W1975064555C116289061 @default.
- W1975064555 hasConceptScore W1975064555C126322002 @default.
- W1975064555 hasConceptScore W1975064555C134018914 @default.
- W1975064555 hasConceptScore W1975064555C170493617 @default.
- W1975064555 hasConceptScore W1975064555C207723603 @default.
- W1975064555 hasConceptScore W1975064555C33789571 @default.
- W1975064555 hasConceptScore W1975064555C47488739 @default.
- W1975064555 hasConceptScore W1975064555C64123433 @default.
- W1975064555 hasConceptScore W1975064555C64615621 @default.
- W1975064555 hasConceptScore W1975064555C71924100 @default.
- W1975064555 hasIssue "5" @default.
- W1975064555 hasLocation W19750645551 @default.
- W1975064555 hasLocation W19750645552 @default.
- W1975064555 hasOpenAccess W1975064555 @default.
- W1975064555 hasPrimaryLocation W19750645551 @default.
- W1975064555 hasRelatedWork W1564402858 @default.
- W1975064555 hasRelatedWork W1972958653 @default.
- W1975064555 hasRelatedWork W1991634597 @default.
- W1975064555 hasRelatedWork W1999663284 @default.
- W1975064555 hasRelatedWork W2000618992 @default.
- W1975064555 hasRelatedWork W2000801970 @default.
- W1975064555 hasRelatedWork W2014913952 @default.
- W1975064555 hasRelatedWork W2023374499 @default.
- W1975064555 hasRelatedWork W3144716053 @default.
- W1975064555 hasRelatedWork W657142851 @default.
- W1975064555 hasVolume "6" @default.
- W1975064555 isParatext "false" @default.
- W1975064555 isRetracted "false" @default.
- W1975064555 magId "1975064555" @default.
- W1975064555 workType "article" @default.