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• W1975103777 endingPage "756" @default.
• W1975103777 startingPage "749" @default.
• W1975103777 abstract "We have investigated the expression of intermediate filament proteins in the developing mouse retina by immunohistochemistry. Antibodies against α-internexin, the three neurofilament subunits (NF-L, NF-M, NF-H), vimentin, and glial fibrillary acidic protein (GFAP) were used to determine the relative expression of these proteins at different post-natal stages of mouse retinal development. α-Internexin is widely distributed in the processes of amacrine cells, horizontal cells and retinal ganglion cells before post-natal day 5 (P5). At this age, NF-L and NF-M are detected primarily in the processes of horizontal cells and retinal ganglion cells, but are rarely found in amacrine cell processes. After P5, α-internexin is found to colocalize with other neuronal intermediate filaments in the cell processes of horizontal and ganglion cells, but its expression is barely detectable in amacrine cells processes. NF-H is not encountered in either the horizontal cell processes or the ganglion nerve fibers until P5. Vimentin is present in all glial cells (astrocytes and Müller cells) and some horizontal cell processes during development, while GFAP is found only in astrocyte processes of the mature retina. The transient presence of α-internexin in amacrine cells only in early development suggests that the protein may play a role in the plasticity of neuronal connections in the retina." @default.
• W1975103777 created "2016-06-24" @default.
• W1975103777 creator A5010579083 @default.
• W1975103777 creator A5015810346 @default.
• W1975103777 date "1995-12-01" @default.
• W1975103777 modified "2023-10-18" @default.
• W1975103777 title "The neuronal intermediate filament, α-internexin is transiently expressed in amacrine cells in the developing mouse retina" @default.
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• W1975103777 doi "https://doi.org/10.1016/s0014-4835(05)80026-0" @default.
• W1975103777 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8846847" @default.
• W1975103777 hasPublicationYear "1995" @default.
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