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- W1975129126 abstract "A new Au(III)-catalyzed tandem amination–hydration reaction has been discovered, leading to the formation of α-(N-2-pyridonyl)ketones and heterocyclic analogues in good to excellent yields (14 examples, 48–90%). This reaction demonstrates the unusual use of a heterocyclic sp2 nitrogen nucleophile in a gold-catalyzed 6-endo-dig cyclization. The tandem process allows rapid access to α-(N-2-pyridonyl)ketones, making them a convenient building block for the synthesis of more complex N-alkyl pyridone targets." @default.
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- W1975129126 date "2012-01-11" @default.
- W1975129126 modified "2023-10-12" @default.
- W1975129126 title "Au(III)-Catalyzed Tandem Amination–Hydration of Alkynes: Synthesis of α-(<i>N</i>-2-Pyridonyl)ketones" @default.
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- W1975129126 doi "https://doi.org/10.1021/ol203398e" @default.
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