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- W1975156661 abstract "<b><i>Background:</i></b> Cancer-related pain is a common problem that may be intractable by medical and neuromodulatory treatment. The dorsal root entry zone (DREZ) is a hyperactive focus in neuropathic pain syndromes, and DREZotomy has been used in selective cases of neuropathic cancer pain. <b><i>Objective:</i></b> The aim of this study was to describe the technique of spinal DREZotomy in the treatment of cancer pain and review the relevant published literature. <b><i>Methods:</i></b> A PubMed database search for ‘DREZ’, ‘dorsal root entry zone’ and ‘cancer’, and a search of the references of these manuscripts, was undertaken. <b><i>Results:</i></b> 14 papers were identified and reviewed that described a total of 123 patients with cancer pain or radiation-induced pain who have been treated with DREZotomy. Though heterogeneous, these studies reported an overall favorable outcome in carefully selected patients with topographically limited pain syndromes. <b><i>Conclusion:</i></b> For patients with well-localized neuropathic cancer pain intractable to medical and first-line surgical management, DREZotomy is a viable treatment option. Further prospective studies are needed to evaluate the outcomes of this procedure." @default.
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- W1975156661 date "2012-01-01" @default.
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- W1975156661 title "DREZotomy in the Treatment of Cancer Pain: A Review" @default.
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- W1975156661 doi "https://doi.org/10.1159/000341072" @default.
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