Matches in SemOpenAlex for { <https://semopenalex.org/work/W1975190713> ?p ?o ?g. }
- W1975190713 endingPage "264" @default.
- W1975190713 startingPage "258" @default.
- W1975190713 abstract "Both mutations caused a reduced affinity for actin, with the W3N replacement having the most pronounced effect. This shows that structural changes in the poly( l ‐proline)‐binding region of profilin can affect the distantly located actin‐binding site. Thus, ligands influencing the structure of the poly( l ‐proline)‐binding site may regulate actin polymerization through profilin. This is consonant with the finding that PIP2, which changes the tryptophan fluorescence in wild‐type profilin and dissociates the profilin:actin complex in vitro, binds more strongly to the W3N mutant profilin. Thus, the poly( l ‐proline)‐binding surface represents a crucial regulatory site of profilin function." @default.
- W1975190713 created "2016-06-24" @default.
- W1975190713 creator A5009247666 @default.
- W1975190713 creator A5012995011 @default.
- W1975190713 creator A5028510592 @default.
- W1975190713 creator A5038220111 @default.
- W1975190713 creator A5066730926 @default.
- W1975190713 date "1997-12-01" @default.
- W1975190713 modified "2023-09-25" @default.
- W1975190713 title "Isolation and characterization of two mutants of human profilin I that do not bind poly(<scp>l</scp>-proline)" @default.
- W1975190713 cites W1555253886 @default.
- W1975190713 cites W1576016596 @default.
- W1975190713 cites W1764042851 @default.
- W1975190713 cites W1921408963 @default.
- W1975190713 cites W1964911409 @default.
- W1975190713 cites W1967505674 @default.
- W1975190713 cites W1970195231 @default.
- W1975190713 cites W1975541739 @default.
- W1975190713 cites W1976121619 @default.
- W1975190713 cites W1995340790 @default.
- W1975190713 cites W2004029773 @default.
- W1975190713 cites W2008036997 @default.
- W1975190713 cites W2011017251 @default.
- W1975190713 cites W2015704602 @default.
- W1975190713 cites W2018212620 @default.
- W1975190713 cites W2023410605 @default.
- W1975190713 cites W2024171558 @default.
- W1975190713 cites W2030442372 @default.
- W1975190713 cites W2031606976 @default.
- W1975190713 cites W2034660356 @default.
- W1975190713 cites W2036754828 @default.
- W1975190713 cites W2040209642 @default.
- W1975190713 cites W2042069042 @default.
- W1975190713 cites W2042480923 @default.
- W1975190713 cites W2044548055 @default.
- W1975190713 cites W2050759207 @default.
- W1975190713 cites W2051281022 @default.
- W1975190713 cites W2051818122 @default.
- W1975190713 cites W2052369011 @default.
- W1975190713 cites W2054446803 @default.
- W1975190713 cites W2054458082 @default.
- W1975190713 cites W2063515244 @default.
- W1975190713 cites W2070072236 @default.
- W1975190713 cites W2071066941 @default.
- W1975190713 cites W2073125687 @default.
- W1975190713 cites W2075103819 @default.
- W1975190713 cites W2087735445 @default.
- W1975190713 cites W2090112453 @default.
- W1975190713 cites W2090217559 @default.
- W1975190713 cites W2090521307 @default.
- W1975190713 cites W2107937825 @default.
- W1975190713 cites W2125682735 @default.
- W1975190713 cites W2127612017 @default.
- W1975190713 cites W2138270253 @default.
- W1975190713 cites W2888511473 @default.
- W1975190713 cites W4237159918 @default.
- W1975190713 cites W4297917728 @default.
- W1975190713 doi "https://doi.org/10.1016/s0014-5793(97)01376-8" @default.
- W1975190713 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9428724" @default.
- W1975190713 hasPublicationYear "1997" @default.
- W1975190713 type Work @default.
- W1975190713 sameAs 1975190713 @default.
- W1975190713 citedByCount "41" @default.
- W1975190713 countsByYear W19751907132013 @default.
- W1975190713 countsByYear W19751907132014 @default.
- W1975190713 countsByYear W19751907132015 @default.
- W1975190713 countsByYear W19751907132018 @default.
- W1975190713 countsByYear W19751907132019 @default.
- W1975190713 countsByYear W19751907132020 @default.
- W1975190713 countsByYear W19751907132021 @default.
- W1975190713 countsByYear W19751907132022 @default.
- W1975190713 crossrefType "journal-article" @default.
- W1975190713 hasAuthorship W1975190713A5009247666 @default.
- W1975190713 hasAuthorship W1975190713A5012995011 @default.
- W1975190713 hasAuthorship W1975190713A5028510592 @default.
- W1975190713 hasAuthorship W1975190713A5038220111 @default.
- W1975190713 hasAuthorship W1975190713A5066730926 @default.
- W1975190713 hasBestOaLocation W19751907131 @default.
- W1975190713 hasConcept C104317684 @default.
- W1975190713 hasConcept C107824862 @default.
- W1975190713 hasConcept C125705527 @default.
- W1975190713 hasConcept C142669718 @default.
- W1975190713 hasConcept C143065580 @default.
- W1975190713 hasConcept C1491633281 @default.
- W1975190713 hasConcept C185592680 @default.
- W1975190713 hasConcept C203253989 @default.
- W1975190713 hasConcept C2779815552 @default.
- W1975190713 hasConcept C2993400109 @default.
- W1975190713 hasConcept C515207424 @default.
- W1975190713 hasConcept C55493867 @default.
- W1975190713 hasConcept C59999672 @default.
- W1975190713 hasConcept C86803240 @default.
- W1975190713 hasConceptScore W1975190713C104317684 @default.
- W1975190713 hasConceptScore W1975190713C107824862 @default.
- W1975190713 hasConceptScore W1975190713C125705527 @default.
- W1975190713 hasConceptScore W1975190713C142669718 @default.
- W1975190713 hasConceptScore W1975190713C143065580 @default.
- W1975190713 hasConceptScore W1975190713C1491633281 @default.