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- W1975287581 abstract "Caring for cartilage: A potent and selective matrix metalloproteinase-13 (MMP-13) inhibitor has been discovered with a novel 2-benzisothiazolylimino-5-benzylidenethiazolidin-4-one scaffold. The structure–activity relationships of the three positional methoxybenzylidene isomers with respect to their chondroprotective effects was evaluated. Molecular modeling provided insight into the binding mode of these non-zinc-chelating (allosteric) inhibitors with MMP-13." @default.
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- W1975287581 date "2011-06-09" @default.
- W1975287581 modified "2023-09-23" @default.
- W1975287581 title "Benzisothiazolyliminothiazolidin-4-ones with Chondroprotective Properties: Searching for Potent and Selective Inhibitors of MMP-13" @default.
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- W1975287581 doi "https://doi.org/10.1002/cmdc.201100223" @default.
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