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- W1975288333 abstract "Histological studies were correlated with developmentally regulated isoenzyme transitions of creatine kinase (CK) in free soleus muscle grafts in mice, 1–25 days after operation. One series of muscles was treated with Marcaine, a myotoxin, in order to promote subsequent regeneration of the muscle. Another set of muscles was mock-treated. In both series of experiments, CK-BB and hybrid CK-MB isoenzymes reappeared transiently as the myoblasts fused and the muscle regenerated. CK isoenzyme transitions were somewhat more pronounced in Marcaine-treated muscle. Nine days after grafting the muscle, specific CK-MM was again present almost exclusively. In this regenerating system, therefore, isoenzyme transitions correlate with histologically detectable regenerative changes, recapitulating the events of embryonic muscle development." @default.
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- W1975288333 date "1982-05-01" @default.
- W1975288333 modified "2023-09-27" @default.
- W1975288333 title "Creatine kinase isoenzyme transitions in muscle grafts of mice" @default.
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- W1975288333 doi "https://doi.org/10.1016/0045-6039(82)90004-5" @default.
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