Matches in SemOpenAlex for { <https://semopenalex.org/work/W1975331683> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W1975331683 abstract "The reasons for the existence of two gas phase conformers for electrosprayed ions of the large tetradecameric protein complex GroEL are considered. Key features are that: (1) both conformers extrapolate to very similar cross sections in the limit of zero charge; (2) both conformers supercharge above the maximum value permitted by the Rayleigh criterion; and (3) one of the conformers supercharges substantially more than the other. We hypothesize that the supercharging observed is associated to the approximately cylindrical shape of GroEL in aqueous solution, enabling accumulation of extra charge on either one or two of its bases when they intersect the evaporating drop surface. The two conformers would then correspond to cases when either one or the two bases of the cylinder carry extra charge. Apparently, the conformer symmetrically (doubly) supercharged on both ends is Coulombically stretched, therefore exhibiting a mobility different from the conformer asymmetrically supercharged only on one end. Several general consequences follow. First, non-spherical proteins may generally be charged above the usual Rayleigh limit. Second, we confirm the previously advanced but contentious notion that gas phase protein ions are readily compacted or stretched away from their crystal structure by capillary and Coulombic forces during the electrospraying process." @default.
- W1975331683 created "2016-06-24" @default.
- W1975331683 creator A5083401528 @default.
- W1975331683 date "2012-10-06" @default.
- W1975331683 modified "2023-09-24" @default.
- W1975331683 title "Why do GroEL Ions Exhibit Two Gas Phase Conformers?" @default.
- W1975331683 cites W1976824047 @default.
- W1975331683 cites W1978528584 @default.
- W1975331683 cites W1985616855 @default.
- W1975331683 cites W2011304938 @default.
- W1975331683 cites W2016131879 @default.
- W1975331683 cites W2026183640 @default.
- W1975331683 cites W2062351773 @default.
- W1975331683 cites W2065843920 @default.
- W1975331683 cites W2070783701 @default.
- W1975331683 cites W2071992954 @default.
- W1975331683 cites W2084163461 @default.
- W1975331683 cites W2091474459 @default.
- W1975331683 cites W2095111624 @default.
- W1975331683 cites W2126816602 @default.
- W1975331683 cites W2153191658 @default.
- W1975331683 cites W2165192566 @default.
- W1975331683 cites W2314932672 @default.
- W1975331683 cites W2315295879 @default.
- W1975331683 cites W2317233863 @default.
- W1975331683 cites W2951997582 @default.
- W1975331683 doi "https://doi.org/10.1007/s13361-012-0454-3" @default.
- W1975331683 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23055071" @default.
- W1975331683 hasPublicationYear "2012" @default.
- W1975331683 type Work @default.
- W1975331683 sameAs 1975331683 @default.
- W1975331683 citedByCount "6" @default.
- W1975331683 countsByYear W19753316832013 @default.
- W1975331683 countsByYear W19753316832015 @default.
- W1975331683 countsByYear W19753316832019 @default.
- W1975331683 crossrefType "journal-article" @default.
- W1975331683 hasAuthorship W1975331683A5083401528 @default.
- W1975331683 hasBestOaLocation W19753316831 @default.
- W1975331683 hasConcept C104317684 @default.
- W1975331683 hasConcept C145148216 @default.
- W1975331683 hasConcept C159467904 @default.
- W1975331683 hasConcept C178790620 @default.
- W1975331683 hasConcept C185592680 @default.
- W1975331683 hasConcept C18705241 @default.
- W1975331683 hasConcept C32909587 @default.
- W1975331683 hasConcept C41999313 @default.
- W1975331683 hasConcept C44280652 @default.
- W1975331683 hasConcept C547475151 @default.
- W1975331683 hasConcept C55493867 @default.
- W1975331683 hasConcept C8010536 @default.
- W1975331683 hasConcept C87190427 @default.
- W1975331683 hasConceptScore W1975331683C104317684 @default.
- W1975331683 hasConceptScore W1975331683C145148216 @default.
- W1975331683 hasConceptScore W1975331683C159467904 @default.
- W1975331683 hasConceptScore W1975331683C178790620 @default.
- W1975331683 hasConceptScore W1975331683C185592680 @default.
- W1975331683 hasConceptScore W1975331683C18705241 @default.
- W1975331683 hasConceptScore W1975331683C32909587 @default.
- W1975331683 hasConceptScore W1975331683C41999313 @default.
- W1975331683 hasConceptScore W1975331683C44280652 @default.
- W1975331683 hasConceptScore W1975331683C547475151 @default.
- W1975331683 hasConceptScore W1975331683C55493867 @default.
- W1975331683 hasConceptScore W1975331683C8010536 @default.
- W1975331683 hasConceptScore W1975331683C87190427 @default.
- W1975331683 hasLocation W19753316831 @default.
- W1975331683 hasLocation W19753316832 @default.
- W1975331683 hasOpenAccess W1975331683 @default.
- W1975331683 hasPrimaryLocation W19753316831 @default.
- W1975331683 hasRelatedWork W1101246 @default.
- W1975331683 hasRelatedWork W1637565835 @default.
- W1975331683 hasRelatedWork W1965756857 @default.
- W1975331683 hasRelatedWork W1978429200 @default.
- W1975331683 hasRelatedWork W2011420602 @default.
- W1975331683 hasRelatedWork W2012925943 @default.
- W1975331683 hasRelatedWork W2019812098 @default.
- W1975331683 hasRelatedWork W2026001457 @default.
- W1975331683 hasRelatedWork W2028363374 @default.
- W1975331683 hasRelatedWork W2051105271 @default.
- W1975331683 hasRelatedWork W2062628675 @default.
- W1975331683 hasRelatedWork W2066011887 @default.
- W1975331683 hasRelatedWork W2074439322 @default.
- W1975331683 hasRelatedWork W2080248597 @default.
- W1975331683 hasRelatedWork W2119826932 @default.
- W1975331683 hasRelatedWork W2131820445 @default.
- W1975331683 hasRelatedWork W2577200906 @default.
- W1975331683 hasRelatedWork W2778517312 @default.
- W1975331683 hasRelatedWork W3103328453 @default.
- W1975331683 hasRelatedWork W3124495262 @default.
- W1975331683 isParatext "false" @default.
- W1975331683 isRetracted "false" @default.
- W1975331683 magId "1975331683" @default.
- W1975331683 workType "article" @default.