Matches in SemOpenAlex for { <https://semopenalex.org/work/W1975378049> ?p ?o ?g. }
Showing items 1 to 50 of
50
with 100 items per page.
- W1975378049 endingPage "2547" @default.
- W1975378049 startingPage "2547" @default.
- W1975378049 abstract "Consecutive rounds of fecal occult blood tests (FOBTs) are used to screen for colorectal cancer (CRC); they detect precursor lesions and early-stage disease. We assessed whether the positivity rate and the positive predictive values (PPVs) for advanced neoplasia and CRC decrease with repeated testing by using fecal immunochemical tests (FITs).Data were collected from 2 rounds of screening. In the first round, average-risk persons (50 to 74 years old) were randomly assigned to groups that received the guaiac FOBT or FIT. In the second round, the subjects received only FIT (1594 received FIT after guaiac FOBT and 2022 received FIT after FIT). The positivity rate and PPV for advanced neoplasia and CRC were compared between second-round participants with a previous negative test result (FIT after guaiac FOBT or FIT after FIT) and first-round participants (guaiac FOBT or FIT).The rate of positive results from FIT was 7.4% in the FIT-after-FIT group, compared with 8.1% in the first-round FIT group (P = .34). A significant decrease was observed in the PPV for advanced neoplasia between the first and second round from 55% (132/239) to 44% (112/252; P = .017). The PPV for CRC was 8% (20/239) in the first round versus 4% (9/252) in the second round (P = .024). Ten interval cancers were diagnosed. There were no significant differences in stages of cancers detected in the first and second round or the interval cancers.The rate of positive results from FIT does not decrease after repeated CRC screening, but the PPVs of FIT for advanced neoplasia and for CRC are significantly lower among second-round participants who tested negative in the first round." @default.
- W1975378049 created "2016-06-24" @default.
- W1975378049 creator A5063360212 @default.
- W1975378049 date "2000-09-01" @default.
- W1975378049 modified "2023-09-25" @default.
- W1975378049 title "Screening colonoscopy—can we afford the cost?" @default.
- W1975378049 doi "https://doi.org/10.1016/s0002-9270(00)01620-8" @default.
- W1975378049 hasPublicationYear "2000" @default.
- W1975378049 type Work @default.
- W1975378049 sameAs 1975378049 @default.
- W1975378049 citedByCount "0" @default.
- W1975378049 crossrefType "journal-article" @default.
- W1975378049 hasAuthorship W1975378049A5063360212 @default.
- W1975378049 hasConcept C121608353 @default.
- W1975378049 hasConcept C126322002 @default.
- W1975378049 hasConcept C2778435480 @default.
- W1975378049 hasConcept C2779158730 @default.
- W1975378049 hasConcept C44249647 @default.
- W1975378049 hasConcept C526805850 @default.
- W1975378049 hasConcept C71924100 @default.
- W1975378049 hasConcept C90924648 @default.
- W1975378049 hasConceptScore W1975378049C121608353 @default.
- W1975378049 hasConceptScore W1975378049C126322002 @default.
- W1975378049 hasConceptScore W1975378049C2778435480 @default.
- W1975378049 hasConceptScore W1975378049C2779158730 @default.
- W1975378049 hasConceptScore W1975378049C44249647 @default.
- W1975378049 hasConceptScore W1975378049C526805850 @default.
- W1975378049 hasConceptScore W1975378049C71924100 @default.
- W1975378049 hasConceptScore W1975378049C90924648 @default.
- W1975378049 hasIssue "9" @default.
- W1975378049 hasLocation W19753780491 @default.
- W1975378049 hasOpenAccess W1975378049 @default.
- W1975378049 hasPrimaryLocation W19753780491 @default.
- W1975378049 hasRelatedWork W2012333859 @default.
- W1975378049 hasRelatedWork W2060405381 @default.
- W1975378049 hasRelatedWork W2073789655 @default.
- W1975378049 hasRelatedWork W2100334152 @default.
- W1975378049 hasRelatedWork W2370330925 @default.
- W1975378049 hasRelatedWork W2413859922 @default.
- W1975378049 hasRelatedWork W2504012805 @default.
- W1975378049 hasRelatedWork W2556026584 @default.
- W1975378049 hasRelatedWork W3044868632 @default.
- W1975378049 hasRelatedWork W3087237052 @default.
- W1975378049 hasVolume "95" @default.
- W1975378049 isParatext "false" @default.
- W1975378049 isRetracted "false" @default.
- W1975378049 magId "1975378049" @default.
- W1975378049 workType "article" @default.