Matches in SemOpenAlex for { <https://semopenalex.org/work/W1975415672> ?p ?o ?g. }
- W1975415672 endingPage "713" @default.
- W1975415672 startingPage "701" @default.
- W1975415672 abstract "PhoB is a signal transduction response regulator that activates nearly 40 genes in phosphate depletion conditions in E. coli and closely related bacteria. The structure of the PhoB effector domain in complex with its target DNA sequence, or pho box, reveals a novel tandem arrangement in which several monomers bind head to tail to successive 11-base pair direct-repeat sequences, coating one face of a smoothly bent double helix. The protein has a winged helix fold in which the DNA recognition elements comprise helix alpha 3, penetrating the major groove, and a beta hairpin wing interacting with a compressed minor groove via Arg219, tightly sandwiched between the DNA sugar backbones. The transactivation loops protrude laterally in an appropriate orientation to interact with the RNA polymerase sigma(70) subunit, which triggers transcription initiation." @default.
- W1975415672 created "2016-06-24" @default.
- W1975415672 creator A5022411969 @default.
- W1975415672 creator A5023079125 @default.
- W1975415672 creator A5024103091 @default.
- W1975415672 creator A5058526143 @default.
- W1975415672 date "2002-05-01" @default.
- W1975415672 modified "2023-10-11" @default.
- W1975415672 title "Tandem DNA Recognition by PhoB, a Two-Component Signal Transduction Transcriptional Activator" @default.
- W1975415672 cites W133905691 @default.
- W1975415672 cites W1595456170 @default.
- W1975415672 cites W1965456430 @default.
- W1975415672 cites W1969435183 @default.
- W1975415672 cites W1983593130 @default.
- W1975415672 cites W1990896380 @default.
- W1975415672 cites W1995017064 @default.
- W1975415672 cites W2001641653 @default.
- W1975415672 cites W2002099745 @default.
- W1975415672 cites W2005144583 @default.
- W1975415672 cites W2021582328 @default.
- W1975415672 cites W2025617204 @default.
- W1975415672 cites W2028625767 @default.
- W1975415672 cites W2033210346 @default.
- W1975415672 cites W2037898928 @default.
- W1975415672 cites W2056627597 @default.
- W1975415672 cites W2072556211 @default.
- W1975415672 cites W2075709402 @default.
- W1975415672 cites W2080476827 @default.
- W1975415672 cites W2090672353 @default.
- W1975415672 cites W2094002418 @default.
- W1975415672 cites W2098089372 @default.
- W1975415672 cites W2108559568 @default.
- W1975415672 cites W2113518661 @default.
- W1975415672 cites W2115285855 @default.
- W1975415672 cites W2128827381 @default.
- W1975415672 cites W2133335149 @default.
- W1975415672 cites W2142193549 @default.
- W1975415672 cites W2148197128 @default.
- W1975415672 cites W2150482536 @default.
- W1975415672 cites W2151419716 @default.
- W1975415672 cites W2160471420 @default.
- W1975415672 cites W2166884322 @default.
- W1975415672 cites W2167065653 @default.
- W1975415672 cites W2765289022 @default.
- W1975415672 cites W40411707 @default.
- W1975415672 doi "https://doi.org/10.1016/s0969-2126(02)00761-x" @default.
- W1975415672 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12015152" @default.
- W1975415672 hasPublicationYear "2002" @default.
- W1975415672 type Work @default.
- W1975415672 sameAs 1975415672 @default.
- W1975415672 citedByCount "257" @default.
- W1975415672 countsByYear W19754156722012 @default.
- W1975415672 countsByYear W19754156722013 @default.
- W1975415672 countsByYear W19754156722014 @default.
- W1975415672 countsByYear W19754156722015 @default.
- W1975415672 countsByYear W19754156722016 @default.
- W1975415672 countsByYear W19754156722017 @default.
- W1975415672 countsByYear W19754156722018 @default.
- W1975415672 countsByYear W19754156722019 @default.
- W1975415672 countsByYear W19754156722020 @default.
- W1975415672 countsByYear W19754156722021 @default.
- W1975415672 countsByYear W19754156722022 @default.
- W1975415672 countsByYear W19754156722023 @default.
- W1975415672 crossrefType "journal-article" @default.
- W1975415672 hasAuthorship W1975415672A5022411969 @default.
- W1975415672 hasAuthorship W1975415672A5023079125 @default.
- W1975415672 hasAuthorship W1975415672A5024103091 @default.
- W1975415672 hasAuthorship W1975415672A5058526143 @default.
- W1975415672 hasBestOaLocation W19754156721 @default.
- W1975415672 hasConcept C104292427 @default.
- W1975415672 hasConcept C104317684 @default.
- W1975415672 hasConcept C12554922 @default.
- W1975415672 hasConcept C138885662 @default.
- W1975415672 hasConcept C143065580 @default.
- W1975415672 hasConcept C179926584 @default.
- W1975415672 hasConcept C185581394 @default.
- W1975415672 hasConcept C2781196521 @default.
- W1975415672 hasConcept C41895202 @default.
- W1975415672 hasConcept C54355233 @default.
- W1975415672 hasConcept C552990157 @default.
- W1975415672 hasConcept C86803240 @default.
- W1975415672 hasConcept C95444343 @default.
- W1975415672 hasConceptScore W1975415672C104292427 @default.
- W1975415672 hasConceptScore W1975415672C104317684 @default.
- W1975415672 hasConceptScore W1975415672C12554922 @default.
- W1975415672 hasConceptScore W1975415672C138885662 @default.
- W1975415672 hasConceptScore W1975415672C143065580 @default.
- W1975415672 hasConceptScore W1975415672C179926584 @default.
- W1975415672 hasConceptScore W1975415672C185581394 @default.
- W1975415672 hasConceptScore W1975415672C2781196521 @default.
- W1975415672 hasConceptScore W1975415672C41895202 @default.
- W1975415672 hasConceptScore W1975415672C54355233 @default.
- W1975415672 hasConceptScore W1975415672C552990157 @default.
- W1975415672 hasConceptScore W1975415672C86803240 @default.
- W1975415672 hasConceptScore W1975415672C95444343 @default.
- W1975415672 hasIssue "5" @default.
- W1975415672 hasLocation W19754156721 @default.
- W1975415672 hasLocation W19754156722 @default.