Matches in SemOpenAlex for { <https://semopenalex.org/work/W1975443591> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W1975443591 endingPage "67" @default.
- W1975443591 startingPage "64" @default.
- W1975443591 abstract "Ionotropic glutamate receptors (iGluRs) are a critical component of the vertebrate central nervous system and mediate the majority of rapid excitatory neurotransmission. However, iGluRs are not self-regulating molecules and require additional proteins in order to function properly. Understanding the molecular architecture of functional glutamatergic synapses is therefore an important challenge in neurobiology. To address this question, we combine the techniques of genetics, molecular biology and electrophysiology in the nematode Caenorhabditis elegans. To date, genetic analysis has identified a number of genes required to build a glutamatergic synapse, including the CUB-domain transmembrane protein, SOL-1, which is thought to act as an auxiliary subunit that directly modifies iGluR function. Identifying and characterizing new proteins, such as SOL-1, in the relatively simple nervous system of the worm can contribute to our understanding of how more complex vertebrate nervous systems function." @default.
- W1975443591 created "2016-06-24" @default.
- W1975443591 creator A5061667512 @default.
- W1975443591 creator A5066155977 @default.
- W1975443591 date "2006-01-20" @default.
- W1975443591 modified "2023-09-23" @default.
- W1975443591 title "Building a synapse: genetic analysis of glutamatergic neurotransmission" @default.
- W1975443591 cites W1523646668 @default.
- W1975443591 cites W1562307516 @default.
- W1975443591 cites W1570725062 @default.
- W1975443591 cites W1954241012 @default.
- W1975443591 cites W1983218230 @default.
- W1975443591 cites W1995680954 @default.
- W1975443591 cites W1996208391 @default.
- W1975443591 cites W2013714258 @default.
- W1975443591 cites W2031074940 @default.
- W1975443591 cites W2031475422 @default.
- W1975443591 cites W2036313253 @default.
- W1975443591 cites W2054486575 @default.
- W1975443591 cites W2058615553 @default.
- W1975443591 cites W2060253758 @default.
- W1975443591 cites W2069863147 @default.
- W1975443591 cites W2083605893 @default.
- W1975443591 cites W2088777486 @default.
- W1975443591 cites W2090508938 @default.
- W1975443591 cites W2129108032 @default.
- W1975443591 cites W2139503851 @default.
- W1975443591 cites W2150284538 @default.
- W1975443591 cites W2160938187 @default.
- W1975443591 cites W2168384606 @default.
- W1975443591 cites W4297832928 @default.
- W1975443591 doi "https://doi.org/10.1042/bst0340064" @default.
- W1975443591 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16417484" @default.
- W1975443591 hasPublicationYear "2006" @default.
- W1975443591 type Work @default.
- W1975443591 sameAs 1975443591 @default.
- W1975443591 citedByCount "4" @default.
- W1975443591 countsByYear W19754435912013 @default.
- W1975443591 crossrefType "journal-article" @default.
- W1975443591 hasAuthorship W1975443591A5061667512 @default.
- W1975443591 hasAuthorship W1975443591A5066155977 @default.
- W1975443591 hasConcept C112592302 @default.
- W1975443591 hasConcept C115955781 @default.
- W1975443591 hasConcept C127445978 @default.
- W1975443591 hasConcept C169760540 @default.
- W1975443591 hasConcept C170493617 @default.
- W1975443591 hasConcept C17077164 @default.
- W1975443591 hasConcept C200170125 @default.
- W1975443591 hasConcept C2780648746 @default.
- W1975443591 hasConcept C54355233 @default.
- W1975443591 hasConcept C545706735 @default.
- W1975443591 hasConcept C61174792 @default.
- W1975443591 hasConcept C86803240 @default.
- W1975443591 hasConceptScore W1975443591C112592302 @default.
- W1975443591 hasConceptScore W1975443591C115955781 @default.
- W1975443591 hasConceptScore W1975443591C127445978 @default.
- W1975443591 hasConceptScore W1975443591C169760540 @default.
- W1975443591 hasConceptScore W1975443591C170493617 @default.
- W1975443591 hasConceptScore W1975443591C17077164 @default.
- W1975443591 hasConceptScore W1975443591C200170125 @default.
- W1975443591 hasConceptScore W1975443591C2780648746 @default.
- W1975443591 hasConceptScore W1975443591C54355233 @default.
- W1975443591 hasConceptScore W1975443591C545706735 @default.
- W1975443591 hasConceptScore W1975443591C61174792 @default.
- W1975443591 hasConceptScore W1975443591C86803240 @default.
- W1975443591 hasIssue "1" @default.
- W1975443591 hasLocation W19754435911 @default.
- W1975443591 hasLocation W19754435912 @default.
- W1975443591 hasOpenAccess W1975443591 @default.
- W1975443591 hasPrimaryLocation W19754435911 @default.
- W1975443591 hasRelatedWork W1079267665 @default.
- W1975443591 hasRelatedWork W2012070150 @default.
- W1975443591 hasRelatedWork W2022264643 @default.
- W1975443591 hasRelatedWork W2027965057 @default.
- W1975443591 hasRelatedWork W2165898385 @default.
- W1975443591 hasRelatedWork W2274772737 @default.
- W1975443591 hasRelatedWork W2283332353 @default.
- W1975443591 hasRelatedWork W2606715888 @default.
- W1975443591 hasRelatedWork W2971185820 @default.
- W1975443591 hasRelatedWork W3173977232 @default.
- W1975443591 hasVolume "34" @default.
- W1975443591 isParatext "false" @default.
- W1975443591 isRetracted "false" @default.
- W1975443591 magId "1975443591" @default.
- W1975443591 workType "article" @default.