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• W1975488051 abstract "Abstract 1. 1. Flounder intestinal smooth muscle possessed a slow spontaneous contractile rhythm. Both KCl and caffeine induced contractures in the preparation. 2. 2. In both Ca-free EGTA media and in La 3+ salines both spontaneous activity and KCl responses were abolished. 3. 3. Fine structural studies revealed a large extracellular matrix but only a scanty sub-membrane vesicle development. This was mirrored in the Ca 4 5 efflux curve which possessed a large fast component and a small slow component. 4. 4. KCl and La 3+ simulated fibre Ca 4 5 efflux but caffeine was without such effect. At the same time tissue Ca 4 5 uptake was increased by caffeine, reduced by KCl and strongly reduced by La 3+ 5. 5. Tension development in this muscle appears strongly dependent upon an influx of extracellular calcium and intracellular calcium fluxes may play only a minor role in the overall calcium utilization during contraction." @default.
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• W1975488051 date "1979-01-01" @default.
• W1975488051 modified "2023-09-26" @default.
• W1975488051 title "Spontaneous activity and related calcium movements of fish intestinal smooth muscle. The effect of depolarization, caffeine and lanthanum" @default.
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• W1975488051 doi "https://doi.org/10.1016/0306-3623(79)90025-9" @default.
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