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• W1975489675 abstract "The relationship between risk of glioma and alcohol consumption has been widely studied, but results have been conflicting. We therefore conducted a meta-analysis of observational studies to systematically assess the relationship between alcohol drinking and risk of glioma. Two electronic databases (PubMed and EMBASE) were searched from inception to 8 August 2013 to identify pertinent studies that linked alcohol drinking with glioma risk. We used a random-effects model to calculate the overall relative risk (RR) with corresponding 95% confidence intervals (CIs). Fifteen case-control and four cohort studies were identified for this analysis. The combined RR for total alcohol drinkers versus non-drinkers was 0.96 (95% CI: 0.89-1.04). In the subgroup analysis by geographic area, a significant association was observed in North American studies (RR = 0.78, 95% CI: 0.65-0.93), but not in European or Asian/Australian studies. In the subgroup analysis by study design, a borderline significant association emerged in population-based case-control studies (RR = 0.82, 95% CI: 0.68-0.99), but not in hospital-based case-control studies (RR = 1.00, 95% CI: 0.99-1.01) or cohort group (RR = 1.03, 95% CI: 0.88-1.20). Our results show no material association between alcohol consumption and risk of glioma existed. Further prospective evidences are needed to confirm this association." @default.
• W1975489675 created "2016-06-24" @default.
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• W1975489675 date "2014-01-27" @default.
• W1975489675 modified "2023-09-26" @default.
• W1975489675 title "Alcohol Consumption and Risk of Glioma: A Meta-Analysis of 19 Observational Studies" @default.
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• W1975489675 doi "https://doi.org/10.3390/nu6020504" @default.
• W1975489675 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3942713" @default.
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