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- W1975510543 abstract "The HIV-1 Rev response element (RRE) is a ~350 nucleotide, highly structured, cis-acting RNA element essential for viral replication. It is located in the env coding region of the viral genome and is extremely well conserved across different HIV-1 isolates. It is present on all partially spliced and unspliced viral mRNA transcripts, and serves as an RNA framework onto which multiple molecules of the viral protein Rev assemble. The Rev-RRE oligomeric complex mediates the export of these messages from the nucleus to the cytoplasm, where they are translated to produce essential viral proteins and/or packaged as genomes for new virions." @default.
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- W1975510543 date "2012-01-01" @default.
- W1975510543 modified "2023-10-02" @default.
- W1975510543 title "The HIV-1 Rev response element" @default.
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- W1975510543 doi "https://doi.org/10.4161/rna.9.1.18178" @default.
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