FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1975535331> ?p ?o ?g. }

• W1975535331 endingPage "572" @default.
• W1975535331 startingPage "565" @default.
• W1975535331 abstract "Adenocarcinoma (ACA) of the uterine cervix is increasing in incidence and currently accounts for approximately 20% of all cervical malignancies. MicroRNAs (miRNAs) have been investigated as potential biomarkers of cervical cancer; however, their role in ACA remains unknown. Here, we characterized miRNA expression profiles and investigated miRNAs as diagnostic and prognostic factors in ACA.Evaluation of genome-wide miRNA expression profiles in ACA by microarray led to the identification of ten candidate miRNAs, whose expression patterns were validated by qRT-PCR in 45 ACA, 10 normal control, and 15 squamous cell carcinoma samples. The association between miRNA expression and prognosis was analyzed in patients with ACA.Microarray analysis identified 86 miRNAs that were dysregulated more than 2.0-fold (p<0.05) in ACA relative to normal tissues of the uterine cervix. Five most over- and underexpressed miRNAs were selected respectively and their expression patterns were confirmed in the validation set. MiR-135b, miR-192, and miR194 were overexpressed in ACA, and miR-363-3p, miR-195 and miR-199b were significantly associated with conventional prognostic factors. Overexpression of miR-363-3p by more than 2.5-fold relative to the normal control was a strong predictor of favorable prognosis (hazard ratio, 0.1; 95% confidence interval, 0.009-0.779) after adjusting for confounders.MiR-135b, miR-192, and miR-194 are altered in uterine cervical ACA, and miR-363-3p is an independent favorable prognostic factor in ACA. These miRNAs could be of value as biomarkers for the diagnosis and prognosis of ACA." @default.
• W1975535331 created "2016-06-24" @default.
• W1975535331 creator A5004924024 @default.
• W1975535331 creator A5023908455 @default.
• W1975535331 creator A5025030935 @default.
• W1975535331 creator A5031624814 @default.
• W1975535331 creator A5035365662 @default.
• W1975535331 creator A5047550774 @default.
• W1975535331 creator A5066751142 @default.
• W1975535331 creator A5091338787 @default.
• W1975535331 date "2014-12-01" @default.
• W1975535331 modified "2023-10-05" @default.
• W1975535331 title "Dysregulated microRNA expression in adenocarcinoma of the uterine cervix: Clinical impact of miR-363-3p" @default.
• W1975535331 cites W144423133 @default.
• W1975535331 cites W1967229727 @default.
• W1975535331 cites W1970858874 @default.
• W1975535331 cites W1981299401 @default.
• W1975535331 cites W1982973163 @default.
• W1975535331 cites W1989691542 @default.
• W1975535331 cites W1992303379 @default.
• W1975535331 cites W2002995168 @default.
• W1975535331 cites W2006797972 @default.
• W1975535331 cites W2028496196 @default.
• W1975535331 cites W2030572260 @default.
• W1975535331 cites W2046930479 @default.
• W1975535331 cites W2052599765 @default.
• W1975535331 cites W2061975704 @default.
• W1975535331 cites W2070633280 @default.
• W1975535331 cites W2073039728 @default.
• W1975535331 cites W2076060004 @default.
• W1975535331 cites W2076721289 @default.
• W1975535331 cites W2077327925 @default.
• W1975535331 cites W2080390072 @default.
• W1975535331 cites W2093054447 @default.
• W1975535331 cites W2100651747 @default.
• W1975535331 cites W2101541945 @default.
• W1975535331 cites W2106945904 @default.
• W1975535331 cites W2120405223 @default.
• W1975535331 cites W2122760943 @default.
• W1975535331 cites W2123827665 @default.
• W1975535331 cites W2130808338 @default.
• W1975535331 cites W2130979840 @default.
• W1975535331 cites W2133409869 @default.
• W1975535331 cites W2135045906 @default.
• W1975535331 cites W2135779855 @default.
• W1975535331 cites W2142188958 @default.
• W1975535331 cites W2155391095 @default.
• W1975535331 cites W2158217645 @default.
• W1975535331 cites W2160918828 @default.
• W1975535331 doi "https://doi.org/10.1016/j.ygyno.2014.09.010" @default.
• W1975535331 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25230213" @default.
• W1975535331 hasPublicationYear "2014" @default.
• W1975535331 type Work @default.
• W1975535331 sameAs 1975535331 @default.
• W1975535331 citedByCount "28" @default.
• W1975535331 countsByYear W19755353312015 @default.
• W1975535331 countsByYear W19755353312016 @default.
• W1975535331 countsByYear W19755353312017 @default.
• W1975535331 countsByYear W19755353312018 @default.
• W1975535331 countsByYear W19755353312019 @default.
• W1975535331 countsByYear W19755353312020 @default.
• W1975535331 countsByYear W19755353312021 @default.
• W1975535331 countsByYear W19755353312022 @default.
• W1975535331 countsByYear W19755353312023 @default.
• W1975535331 crossrefType "journal-article" @default.
• W1975535331 hasAuthorship W1975535331A5004924024 @default.
• W1975535331 hasAuthorship W1975535331A5023908455 @default.
• W1975535331 hasAuthorship W1975535331A5025030935 @default.
• W1975535331 hasAuthorship W1975535331A5031624814 @default.
• W1975535331 hasAuthorship W1975535331A5035365662 @default.
• W1975535331 hasAuthorship W1975535331A5047550774 @default.
• W1975535331 hasAuthorship W1975535331A5066751142 @default.
• W1975535331 hasAuthorship W1975535331A5091338787 @default.
• W1975535331 hasConcept C104317684 @default.
• W1975535331 hasConcept C121608353 @default.
• W1975535331 hasConcept C126322002 @default.
• W1975535331 hasConcept C143998085 @default.
• W1975535331 hasConcept C145059251 @default.
• W1975535331 hasConcept C150194340 @default.
• W1975535331 hasConcept C186836561 @default.
• W1975535331 hasConcept C207103383 @default.
• W1975535331 hasConcept C2777740455 @default.
• W1975535331 hasConcept C2778220009 @default.
• W1975535331 hasConcept C2781182431 @default.
• W1975535331 hasConcept C44249647 @default.
• W1975535331 hasConcept C502942594 @default.
• W1975535331 hasConcept C50382708 @default.
• W1975535331 hasConcept C54355233 @default.
• W1975535331 hasConcept C71924100 @default.
• W1975535331 hasConcept C86803240 @default.
• W1975535331 hasConceptScore W1975535331C104317684 @default.
• W1975535331 hasConceptScore W1975535331C121608353 @default.
• W1975535331 hasConceptScore W1975535331C126322002 @default.
• W1975535331 hasConceptScore W1975535331C143998085 @default.
• W1975535331 hasConceptScore W1975535331C145059251 @default.
• W1975535331 hasConceptScore W1975535331C150194340 @default.
• W1975535331 hasConceptScore W1975535331C186836561 @default.
• W1975535331 hasConceptScore W1975535331C207103383 @default.

• next