Matches in SemOpenAlex for { <https://semopenalex.org/work/W1975644966> ?p ?o ?g. }
- W1975644966 endingPage "114" @default.
- W1975644966 startingPage "106" @default.
- W1975644966 abstract "Guanine (G)-rich sequences can form a noncanonical four-stranded structure known as the G-quadruplex. G-quadruplex structures are interesting because of their potential biological properties and use in nanosciences. Here, we describe a method to prepare highly stable G-quadruplexes by linking four G-rich DNA strands to form a monomolecular G-quadruplex. In this method, one strand is synthesized first, and then a trebler molecule is added to simultaneously assemble the remaining three strands. This approach allows the introduction of specific modifications in only one of the strands. As a proof of concept, we prepared a quadruplex where one of the chains includes a change in polarity. A hybrid quadruplex is observed in ammonium acetate solutions, whereas in the presence of sodium or potassium, a parallel G-quadruplex structure is formed. In addition to the expected monomolecular quadruplexes, we observed the presence of dimeric G-quadruplex structures. We also applied the method to prepare G-quadruplexes containing a single 8-aminoguanine substitution and found that this single base stabilizes the G-quadruplex structure when located at an internal position." @default.
- W1975644966 created "2016-06-24" @default.
- W1975644966 creator A5013458899 @default.
- W1975644966 creator A5017018844 @default.
- W1975644966 creator A5025885734 @default.
- W1975644966 creator A5037350543 @default.
- W1975644966 creator A5048517749 @default.
- W1975644966 creator A5062566652 @default.
- W1975644966 creator A5081031126 @default.
- W1975644966 date "2012-04-01" @default.
- W1975644966 modified "2023-10-10" @default.
- W1975644966 title "Synthesis and Structural Characterization of Stable Branched DNA G-Quadruplexes Using the Trebler Phosphoramidite" @default.
- W1975644966 cites W1531002716 @default.
- W1975644966 cites W1964858690 @default.
- W1975644966 cites W1968605089 @default.
- W1975644966 cites W1969039627 @default.
- W1975644966 cites W1971985277 @default.
- W1975644966 cites W1974175020 @default.
- W1975644966 cites W1977875298 @default.
- W1975644966 cites W1981618882 @default.
- W1975644966 cites W1986648841 @default.
- W1975644966 cites W1990635146 @default.
- W1975644966 cites W2002345274 @default.
- W1975644966 cites W2004787540 @default.
- W1975644966 cites W2006092704 @default.
- W1975644966 cites W2010445038 @default.
- W1975644966 cites W2011844193 @default.
- W1975644966 cites W2021340080 @default.
- W1975644966 cites W2022696064 @default.
- W1975644966 cites W2027837264 @default.
- W1975644966 cites W2032698727 @default.
- W1975644966 cites W2037727453 @default.
- W1975644966 cites W2039658297 @default.
- W1975644966 cites W2041384774 @default.
- W1975644966 cites W2042151404 @default.
- W1975644966 cites W2042653191 @default.
- W1975644966 cites W2047409813 @default.
- W1975644966 cites W2052626751 @default.
- W1975644966 cites W2052790851 @default.
- W1975644966 cites W2054915272 @default.
- W1975644966 cites W2055108738 @default.
- W1975644966 cites W2058389647 @default.
- W1975644966 cites W2069356007 @default.
- W1975644966 cites W2080103757 @default.
- W1975644966 cites W2088456802 @default.
- W1975644966 cites W2091876286 @default.
- W1975644966 cites W2092377322 @default.
- W1975644966 cites W2099950187 @default.
- W1975644966 cites W2102158380 @default.
- W1975644966 cites W2103205961 @default.
- W1975644966 cites W2107756193 @default.
- W1975644966 cites W2111271543 @default.
- W1975644966 cites W2113707600 @default.
- W1975644966 cites W2124412534 @default.
- W1975644966 cites W2135117255 @default.
- W1975644966 cites W2159960424 @default.
- W1975644966 cites W2166887613 @default.
- W1975644966 cites W2314111280 @default.
- W1975644966 cites W2952064878 @default.
- W1975644966 cites W4214763515 @default.
- W1975644966 cites W4237146925 @default.
- W1975644966 doi "https://doi.org/10.1002/open.201200009" @default.
- W1975644966 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3922461" @default.
- W1975644966 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24551498" @default.
- W1975644966 hasPublicationYear "2012" @default.
- W1975644966 type Work @default.
- W1975644966 sameAs 1975644966 @default.
- W1975644966 citedByCount "11" @default.
- W1975644966 countsByYear W19756449662013 @default.
- W1975644966 countsByYear W19756449662016 @default.
- W1975644966 countsByYear W19756449662017 @default.
- W1975644966 countsByYear W19756449662019 @default.
- W1975644966 countsByYear W19756449662020 @default.
- W1975644966 crossrefType "journal-article" @default.
- W1975644966 hasAuthorship W1975644966A5013458899 @default.
- W1975644966 hasAuthorship W1975644966A5017018844 @default.
- W1975644966 hasAuthorship W1975644966A5025885734 @default.
- W1975644966 hasAuthorship W1975644966A5037350543 @default.
- W1975644966 hasAuthorship W1975644966A5048517749 @default.
- W1975644966 hasAuthorship W1975644966A5062566652 @default.
- W1975644966 hasAuthorship W1975644966A5081031126 @default.
- W1975644966 hasBestOaLocation W19756449661 @default.
- W1975644966 hasConcept C104317684 @default.
- W1975644966 hasConcept C129312508 @default.
- W1975644966 hasConcept C178790620 @default.
- W1975644966 hasConcept C179998833 @default.
- W1975644966 hasConcept C185581394 @default.
- W1975644966 hasConcept C185592680 @default.
- W1975644966 hasConcept C21951064 @default.
- W1975644966 hasConcept C2776043002 @default.
- W1975644966 hasConcept C2778301229 @default.
- W1975644966 hasConcept C2780782300 @default.
- W1975644966 hasConcept C32909587 @default.
- W1975644966 hasConcept C512185932 @default.
- W1975644966 hasConcept C552990157 @default.
- W1975644966 hasConcept C55493867 @default.
- W1975644966 hasConcept C71240020 @default.
- W1975644966 hasConcept C8010536 @default.