FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1975667437> ?p ?o ?g. }

• W1975667437 endingPage "41" @default.
• W1975667437 startingPage "34" @default.
• W1975667437 abstract "Obesity is associated with changes in adiponectin and pro-inflammatory adipokines. Sodium intake can affect adipokine secretion suggesting a role in cardiovascular dysfunction. We tested if long-term dietary sodium restriction modifies the expression of adiponectin and ameliorates the pro-inflammatory profile of obese, diabetic mice.Db/db mice were randomized to high sodium (HS 1.6% Na+, n = 6) or low sodium (LS 0.03% Na+, n = 8) diet for 16 weeks and compared with lean, db/+ mice on HS diet (n = 8). Insulin levels were 50% lower in the db/db mice on LS diet when compared with HS db/db (p < 0.05). LS diet increased cardiac adiponectin mRNA levels in db/db mice by 5-fold when compared with db/db mice on HS diet and by 2-fold when compared with HS lean mice (both p < 0.01). LS diet increased adiponectin in adipose tissue compared with db/db mice on HS diet, achieving levels similar to those of lean mice. MCP-1, IL-6 and TNF-α expression were reduced more than 50% in adipose tissue of db/db mice on LS diet when compared with HS db/db mice (all p < 0.05), to levels observed in the HS lean mice. Further, LS db/db mice had significantly reduced circulating MCP-1 and IL-6 levels when compared with HS db/db mice (both p < 0.01).In obese-diabetic mice, long-term LS diet increases adiponectin in heart and adipose tissue and reduces pro-inflammatory factors in adipose tissue and plasma. These additive mechanisms may contribute to the potential cardioprotective benefits of LS diet in obesity-related metabolic disorders." @default.
• W1975667437 created "2016-06-24" @default.
• W1975667437 creator A5027552276 @default.
• W1975667437 creator A5031679687 @default.
• W1975667437 creator A5033678258 @default.
• W1975667437 creator A5036314812 @default.
• W1975667437 creator A5039080655 @default.
• W1975667437 creator A5047140893 @default.
• W1975667437 creator A5048806317 @default.
• W1975667437 creator A5060694047 @default.
• W1975667437 date "2014-01-01" @default.
• W1975667437 modified "2023-10-03" @default.
• W1975667437 title "Long-term dietary sodium restriction increases adiponectin expression and ameliorates the proinflammatory adipokine profile in obesity" @default.
• W1975667437 cites W1965938508 @default.
• W1975667437 cites W1970930655 @default.
• W1975667437 cites W1991826575 @default.
• W1975667437 cites W2020877653 @default.
• W1975667437 cites W2034158808 @default.
• W1975667437 cites W2041272089 @default.
• W1975667437 cites W2051192888 @default.
• W1975667437 cites W2052146004 @default.
• W1975667437 cites W2055500306 @default.
• W1975667437 cites W2091683994 @default.
• W1975667437 cites W2093789227 @default.
• W1975667437 cites W2095778117 @default.
• W1975667437 cites W2100495245 @default.
• W1975667437 cites W2102445277 @default.
• W1975667437 cites W2103018133 @default.
• W1975667437 cites W2106174392 @default.
• W1975667437 cites W2110160919 @default.
• W1975667437 cites W2113511490 @default.
• W1975667437 cites W2113849715 @default.
• W1975667437 cites W2115960319 @default.
• W1975667437 cites W2116529135 @default.
• W1975667437 cites W2128287943 @default.
• W1975667437 cites W2130437841 @default.
• W1975667437 cites W2146303375 @default.
• W1975667437 cites W2154301407 @default.
• W1975667437 cites W2158989213 @default.
• W1975667437 cites W2160723513 @default.
• W1975667437 cites W2162366820 @default.
• W1975667437 cites W2166751358 @default.
• W1975667437 cites W4243964560 @default.
• W1975667437 doi "https://doi.org/10.1016/j.numecd.2013.07.004" @default.
• W1975667437 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4405158" @default.
• W1975667437 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24418377" @default.
• W1975667437 hasPublicationYear "2014" @default.
• W1975667437 type Work @default.
• W1975667437 sameAs 1975667437 @default.
• W1975667437 citedByCount "19" @default.
• W1975667437 countsByYear W19756674372014 @default.
• W1975667437 countsByYear W19756674372015 @default.
• W1975667437 countsByYear W19756674372016 @default.
• W1975667437 countsByYear W19756674372017 @default.
• W1975667437 countsByYear W19756674372018 @default.
• W1975667437 countsByYear W19756674372019 @default.
• W1975667437 countsByYear W19756674372021 @default.
• W1975667437 countsByYear W19756674372022 @default.
• W1975667437 crossrefType "journal-article" @default.
• W1975667437 hasAuthorship W1975667437A5027552276 @default.
• W1975667437 hasAuthorship W1975667437A5031679687 @default.
• W1975667437 hasAuthorship W1975667437A5033678258 @default.
• W1975667437 hasAuthorship W1975667437A5036314812 @default.
• W1975667437 hasAuthorship W1975667437A5039080655 @default.
• W1975667437 hasAuthorship W1975667437A5047140893 @default.
• W1975667437 hasAuthorship W1975667437A5048806317 @default.
• W1975667437 hasAuthorship W1975667437A5060694047 @default.
• W1975667437 hasBestOaLocation W19756674372 @default.
• W1975667437 hasConcept C126322002 @default.
• W1975667437 hasConcept C134018914 @default.
• W1975667437 hasConcept C164027704 @default.
• W1975667437 hasConcept C171089720 @default.
• W1975667437 hasConcept C185592680 @default.
• W1975667437 hasConcept C194832188 @default.
• W1975667437 hasConcept C2776782570 @default.
• W1975667437 hasConcept C2776914184 @default.
• W1975667437 hasConcept C2777391703 @default.
• W1975667437 hasConcept C2779306644 @default.
• W1975667437 hasConcept C2780613262 @default.
• W1975667437 hasConcept C511355011 @default.
• W1975667437 hasConcept C71924100 @default.
• W1975667437 hasConceptScore W1975667437C126322002 @default.
• W1975667437 hasConceptScore W1975667437C134018914 @default.
• W1975667437 hasConceptScore W1975667437C164027704 @default.
• W1975667437 hasConceptScore W1975667437C171089720 @default.
• W1975667437 hasConceptScore W1975667437C185592680 @default.
• W1975667437 hasConceptScore W1975667437C194832188 @default.
• W1975667437 hasConceptScore W1975667437C2776782570 @default.
• W1975667437 hasConceptScore W1975667437C2776914184 @default.
• W1975667437 hasConceptScore W1975667437C2777391703 @default.
• W1975667437 hasConceptScore W1975667437C2779306644 @default.
• W1975667437 hasConceptScore W1975667437C2780613262 @default.
• W1975667437 hasConceptScore W1975667437C511355011 @default.
• W1975667437 hasConceptScore W1975667437C71924100 @default.
• W1975667437 hasIssue "1" @default.
• W1975667437 hasLocation W19756674371 @default.
• W1975667437 hasLocation W19756674372 @default.
• W1975667437 hasLocation W19756674373 @default.

• next