Matches in SemOpenAlex for { <https://semopenalex.org/work/W1975682339> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W1975682339 endingPage "S5" @default.
- W1975682339 startingPage "S5" @default.
- W1975682339 abstract "The ability of gonadal steroids to modulate hypothalamic-pituitary-adrenal (HPA) axis function is not well established in humans, but may be of importance in understanding sexual dimorphisms in the stress response. To investigate these effects, we studied normal women (n = 8) and men (n = 5) during pharmacologically-induced hypogonadism and during gonadal steroid replacement. We measured the HPA axis response to three different stimuli: 1) treadmill exercise stress, 2) low-dose dexamethasone suppression test (DST), and 3) ovine corticotropin (oCRH) stimulation. Data were analyzed by analysis of variance with repeated measures (ANOVA-R) and post hoc Bonferroni t tests. Women exhibited a blunted cortisol response to exercise stress (p = 0.05) and increased dexamethasone suppression (p < 0.01) in the hypogonadal compared with the progesterone replaced condition. In men, however, there was no effect of hormonal condition on either the exercise stress or DST results. Exercise stimulated cortisol (p < 0.05) and ACTH (p < 0.01) were significantly increased in men compared with women during the hypogonadal condition. Finally, a significant (p < 0.05) increase in o-CRH stimulated ACTH was seen in men during testosterone replacement. Gonadal steroids appear to more actively regulate HPA axis function in women than men, and the appearance of dimorphic response to exercise under hypogonadal conditions may imply an organizational origin to these gender-related differences." @default.
- W1975682339 created "2016-06-24" @default.
- W1975682339 creator A5000280765 @default.
- W1975682339 creator A5005497098 @default.
- W1975682339 creator A5032335007 @default.
- W1975682339 creator A5046164327 @default.
- W1975682339 creator A5049359413 @default.
- W1975682339 creator A5053070044 @default.
- W1975682339 creator A5065038776 @default.
- W1975682339 creator A5091255598 @default.
- W1975682339 date "2000-04-01" @default.
- W1975682339 modified "2023-10-16" @default.
- W1975682339 title "14. Effects of gonadal steroids on the HPA axis response to stress" @default.
- W1975682339 doi "https://doi.org/10.1016/s0006-3223(00)00267-5" @default.
- W1975682339 hasPublicationYear "2000" @default.
- W1975682339 type Work @default.
- W1975682339 sameAs 1975682339 @default.
- W1975682339 citedByCount "0" @default.
- W1975682339 crossrefType "journal-article" @default.
- W1975682339 hasAuthorship W1975682339A5000280765 @default.
- W1975682339 hasAuthorship W1975682339A5005497098 @default.
- W1975682339 hasAuthorship W1975682339A5032335007 @default.
- W1975682339 hasAuthorship W1975682339A5046164327 @default.
- W1975682339 hasAuthorship W1975682339A5049359413 @default.
- W1975682339 hasAuthorship W1975682339A5053070044 @default.
- W1975682339 hasAuthorship W1975682339A5065038776 @default.
- W1975682339 hasAuthorship W1975682339A5091255598 @default.
- W1975682339 hasConcept C105083479 @default.
- W1975682339 hasConcept C126322002 @default.
- W1975682339 hasConcept C134018914 @default.
- W1975682339 hasConcept C146819174 @default.
- W1975682339 hasConcept C15744967 @default.
- W1975682339 hasConcept C24998067 @default.
- W1975682339 hasConcept C2778575703 @default.
- W1975682339 hasConcept C2779146795 @default.
- W1975682339 hasConcept C2779279991 @default.
- W1975682339 hasConcept C2780401358 @default.
- W1975682339 hasConcept C2780841215 @default.
- W1975682339 hasConcept C71315377 @default.
- W1975682339 hasConcept C71924100 @default.
- W1975682339 hasConcept C99476002 @default.
- W1975682339 hasConceptScore W1975682339C105083479 @default.
- W1975682339 hasConceptScore W1975682339C126322002 @default.
- W1975682339 hasConceptScore W1975682339C134018914 @default.
- W1975682339 hasConceptScore W1975682339C146819174 @default.
- W1975682339 hasConceptScore W1975682339C15744967 @default.
- W1975682339 hasConceptScore W1975682339C24998067 @default.
- W1975682339 hasConceptScore W1975682339C2778575703 @default.
- W1975682339 hasConceptScore W1975682339C2779146795 @default.
- W1975682339 hasConceptScore W1975682339C2779279991 @default.
- W1975682339 hasConceptScore W1975682339C2780401358 @default.
- W1975682339 hasConceptScore W1975682339C2780841215 @default.
- W1975682339 hasConceptScore W1975682339C71315377 @default.
- W1975682339 hasConceptScore W1975682339C71924100 @default.
- W1975682339 hasConceptScore W1975682339C99476002 @default.
- W1975682339 hasIssue "8" @default.
- W1975682339 hasLocation W19756823391 @default.
- W1975682339 hasOpenAccess W1975682339 @default.
- W1975682339 hasPrimaryLocation W19756823391 @default.
- W1975682339 hasRelatedWork W1549089891 @default.
- W1975682339 hasRelatedWork W1976035881 @default.
- W1975682339 hasRelatedWork W1988418183 @default.
- W1975682339 hasRelatedWork W1998979058 @default.
- W1975682339 hasRelatedWork W2003997084 @default.
- W1975682339 hasRelatedWork W2013285984 @default.
- W1975682339 hasRelatedWork W2027210979 @default.
- W1975682339 hasRelatedWork W2080960184 @default.
- W1975682339 hasRelatedWork W2135117278 @default.
- W1975682339 hasRelatedWork W2143812619 @default.
- W1975682339 hasVolume "47" @default.
- W1975682339 isParatext "false" @default.
- W1975682339 isRetracted "false" @default.
- W1975682339 magId "1975682339" @default.
- W1975682339 workType "article" @default.