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- W1975726452 abstract "The T-cell deficiency of nude mice is due to an abnormal differentiation of the thymus epithelium; it can be persistently corrected by grafting a neonatal thymus. However, grafted adult thymuses or epithelial thymuses are not repopulated by large numbers of host-derived lymphocytes, as is the case when a whole neonatal thymus is grafted. Furthermore, the repopulation of the spleen and lymph nodes by T cells is less pronounced than after whole neonatal thymus transplantation, and the restoration of the reactivity to T-cell mitogens is irregular. Therefore, the integrity and the age of the thymus graft are important for a good restoration of the T-lymphoid system of congenitally athymic animals." @default.
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- W1975726452 date "1977-03-01" @default.
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- W1975726452 title "The restoration of the T-lymphoid system of nude mice: Lower efficiency of nonlymphoid, epithelial thymus grafts" @default.
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- W1975726452 doi "https://doi.org/10.1016/0008-8749(77)90289-1" @default.
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