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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1975771569> ?p ?o ?g. }

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• W1975771569 startingPage "85" @default.
• W1975771569 abstract "Our previous study demonstrated that CopA3, a disulfide dimer of the coprisin peptide analogue (LLCIALRKK), has antibacterial activity. In this study, we assessed whether CopA3 caused cellular toxicity in various mammalian cell lines. CopA3 selectively caused a marked decrease in cell viability in Jurkat T, U937, and AML-2 cells (human leukemia cells), but was not cytotoxic to Caki or Hela cells. Fragmentation of DNA, a marker of apoptosis, was also confirmed in the leukemia cell lines, but not in the other cells. CopA3-induced apoptosis in leukemia cells was mediated by apoptosis inducing factor (AIF), indicating induction of a caspase-independent signaling pathway." @default.
• W1975771569 created "2016-06-24" @default.
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• W1975771569 date "2012-02-29" @default.
• W1975771569 modified "2023-10-12" @default.
• W1975771569 title "CopA3 peptide from Copris tripartitus induces apoptosis in human leukemia cells via a caspase-independent pathway" @default.
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• W1975771569 doi "https://doi.org/10.5483/bmbrep.2012.45.2.85" @default.
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