Matches in SemOpenAlex for { <https://semopenalex.org/work/W1975772013> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W1975772013 endingPage "639" @default.
- W1975772013 startingPage "634" @default.
- W1975772013 abstract "The effects of propofol and thiopentone on myocardial contractility and global ischaemia were evaluated using an isolated non-working perfused rat heart preparation. Contractility was assessed using a tension transducer linked to the cardiac apex, and the contractility was expressed as a ratio of the deflection size before and after infusion of the drug. Ischaemia-induced leakage of myocardial proteins and ions (potassium and magnesium) was assessed by comparing the concentrations in the effluent perfusate immediately before and after 60 min of isothermic ischaemia, in the presence of propofol, thiopentone or plain Krebs’ buffer solution (control). Mean contractility ratios of 1.15 and 1.3 were obtained with control and propofol groups respectively (NS), but were reduced to 0.5 in the thiopentone group (P < 0.001). The magnitude of the postischaemic leakage of proteins and potassium was similar in each group; however, the post-ischaemic leakage of magnesium was greater in the thiopentone group than in the propofol or control groups. These data suggest that, compared with thiopentone, propofol is not a potent negative inotrope, and that it may cause less disturbance of myocardial magnesium homeostasis during myocardial ischaemia." @default.
- W1975772013 created "2016-06-24" @default.
- W1975772013 creator A5011460007 @default.
- W1975772013 creator A5041777869 @default.
- W1975772013 creator A5050843268 @default.
- W1975772013 date "1991-07-01" @default.
- W1975772013 modified "2023-10-16" @default.
- W1975772013 title "Myocardial contractility and ischaemia in the isolated perfused rat heart with propofol and thiopentone" @default.
- W1975772013 cites W135110292 @default.
- W1975772013 cites W1965392254 @default.
- W1975772013 cites W1973516682 @default.
- W1975772013 cites W1986086928 @default.
- W1975772013 cites W2022926943 @default.
- W1975772013 cites W2035624164 @default.
- W1975772013 cites W2041590182 @default.
- W1975772013 cites W2060434730 @default.
- W1975772013 cites W2060831383 @default.
- W1975772013 cites W2064742824 @default.
- W1975772013 cites W2068573903 @default.
- W1975772013 cites W2070835594 @default.
- W1975772013 cites W2085444428 @default.
- W1975772013 cites W2093486393 @default.
- W1975772013 cites W2093891211 @default.
- W1975772013 cites W2095652178 @default.
- W1975772013 cites W2097978318 @default.
- W1975772013 cites W2110553287 @default.
- W1975772013 cites W2149456573 @default.
- W1975772013 cites W2274056481 @default.
- W1975772013 cites W2306322519 @default.
- W1975772013 cites W2317533238 @default.
- W1975772013 cites W2337845188 @default.
- W1975772013 cites W2398515249 @default.
- W1975772013 cites W2431284097 @default.
- W1975772013 cites W2994711796 @default.
- W1975772013 cites W4291746756 @default.
- W1975772013 doi "https://doi.org/10.1007/bf03008201" @default.
- W1975772013 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1934218" @default.
- W1975772013 hasPublicationYear "1991" @default.
- W1975772013 type Work @default.
- W1975772013 sameAs 1975772013 @default.
- W1975772013 citedByCount "12" @default.
- W1975772013 countsByYear W19757720132014 @default.
- W1975772013 countsByYear W19757720132015 @default.
- W1975772013 countsByYear W19757720132018 @default.
- W1975772013 countsByYear W19757720132020 @default.
- W1975772013 crossrefType "journal-article" @default.
- W1975772013 hasAuthorship W1975772013A5011460007 @default.
- W1975772013 hasAuthorship W1975772013A5041777869 @default.
- W1975772013 hasAuthorship W1975772013A5050843268 @default.
- W1975772013 hasBestOaLocation W19757720131 @default.
- W1975772013 hasConcept C126322002 @default.
- W1975772013 hasConcept C155710745 @default.
- W1975772013 hasConcept C2776277131 @default.
- W1975772013 hasConcept C39133596 @default.
- W1975772013 hasConcept C42219234 @default.
- W1975772013 hasConcept C519063684 @default.
- W1975772013 hasConcept C541997718 @default.
- W1975772013 hasConcept C71924100 @default.
- W1975772013 hasConceptScore W1975772013C126322002 @default.
- W1975772013 hasConceptScore W1975772013C155710745 @default.
- W1975772013 hasConceptScore W1975772013C2776277131 @default.
- W1975772013 hasConceptScore W1975772013C39133596 @default.
- W1975772013 hasConceptScore W1975772013C42219234 @default.
- W1975772013 hasConceptScore W1975772013C519063684 @default.
- W1975772013 hasConceptScore W1975772013C541997718 @default.
- W1975772013 hasConceptScore W1975772013C71924100 @default.
- W1975772013 hasIssue "5" @default.
- W1975772013 hasLocation W19757720131 @default.
- W1975772013 hasLocation W19757720132 @default.
- W1975772013 hasOpenAccess W1975772013 @default.
- W1975772013 hasPrimaryLocation W19757720131 @default.
- W1975772013 hasRelatedWork W2003286282 @default.
- W1975772013 hasRelatedWork W2008928560 @default.
- W1975772013 hasRelatedWork W2077312822 @default.
- W1975772013 hasRelatedWork W2130792295 @default.
- W1975772013 hasRelatedWork W2170431845 @default.
- W1975772013 hasRelatedWork W2345393050 @default.
- W1975772013 hasRelatedWork W2397284895 @default.
- W1975772013 hasRelatedWork W2436892133 @default.
- W1975772013 hasRelatedWork W2469906278 @default.
- W1975772013 hasRelatedWork W4255494574 @default.
- W1975772013 hasVolume "38" @default.
- W1975772013 isParatext "false" @default.
- W1975772013 isRetracted "false" @default.
- W1975772013 magId "1975772013" @default.
- W1975772013 workType "article" @default.