Matches in SemOpenAlex for { <https://semopenalex.org/work/W1975812457> ?p ?o ?g. }
- W1975812457 endingPage "53" @default.
- W1975812457 startingPage "48" @default.
- W1975812457 abstract "Background Minor cardiac marker elevation after percutaneous coronary intervention has long-term prognostic significance. We examined whether nicorandil, a nicotinamide-nitrate ester, reduces the incidence of minor cardiac marker elevation after coronary stenting. Methods Patients (n=192) undergoing coronary stenting were randomly assigned to receive nicorandil (nicorandil group, n=91) or vehicle (control group, n=101). Nicorandil (2 μg/kg/min, intravenously) was administered immediately after the patients were transferred into the catheterization laboratory and continued for 6 h. We measured the serum concentrations of creatine kinase isoenzyme MB (CK-MB) before, immediately after, and 6, 12, and 24 h after the procedure, and those of cardiac troponin T (cTnT) 24 h after the procedure. Results There was no significant difference in clinical background between the 2 groups. The nicorandil group showed a significantly lower incidence of CK-MB elevation (>1× upper limit of control range, 20 IU/l) than the control group (8.8% vs 21.8%, p<0.05). The levels of serum CK-MB in the nicorandil group were significantly lower than those in the control group (13.4±5.7 vs 16.5±9.7 IU/l, p<0.01). Similarly, the nicorandil group showed a significantly lower incidence of cTnT elevation [>1× (0.1 ng/ml) or >2× (0.2 ng/ml)] upper limit of control range than the control group (14.3% vs 26.7%, p<0.05, or 7.7% vs 17.8%, p<0.05). Serum cTnT levels were also significantly lower in the nicorandil group than in the control group (0.05±0.10 vs 0.15±0.36 ng/ml, p<0.05). Conclusions The results demonstrated that nicorandil reduces minor cardiac marker elevation after coronary stenting." @default.
- W1975812457 created "2016-06-24" @default.
- W1975812457 creator A5005637906 @default.
- W1975812457 creator A5010606352 @default.
- W1975812457 creator A5024822994 @default.
- W1975812457 creator A5025580504 @default.
- W1975812457 creator A5039586274 @default.
- W1975812457 creator A5043160800 @default.
- W1975812457 creator A5052840744 @default.
- W1975812457 creator A5053545087 @default.
- W1975812457 creator A5058553514 @default.
- W1975812457 creator A5087927550 @default.
- W1975812457 date "2006-02-01" @default.
- W1975812457 modified "2023-10-03" @default.
- W1975812457 title "Nicorandil reduces the incidence of minor cardiac marker elevation after coronary stenting" @default.
- W1975812457 cites W1970944108 @default.
- W1975812457 cites W1973056685 @default.
- W1975812457 cites W1979188583 @default.
- W1975812457 cites W1984015236 @default.
- W1975812457 cites W2002525608 @default.
- W1975812457 cites W2002660109 @default.
- W1975812457 cites W2002736917 @default.
- W1975812457 cites W2015266979 @default.
- W1975812457 cites W2025068128 @default.
- W1975812457 cites W2039785113 @default.
- W1975812457 cites W2040393337 @default.
- W1975812457 cites W2049211920 @default.
- W1975812457 cites W2053420049 @default.
- W1975812457 cites W2058163722 @default.
- W1975812457 cites W2060171297 @default.
- W1975812457 cites W2064226555 @default.
- W1975812457 cites W2069316898 @default.
- W1975812457 cites W2071330170 @default.
- W1975812457 cites W2077014318 @default.
- W1975812457 cites W2078113728 @default.
- W1975812457 cites W2086626309 @default.
- W1975812457 cites W2090566923 @default.
- W1975812457 cites W2091843163 @default.
- W1975812457 cites W2098885552 @default.
- W1975812457 cites W2102300355 @default.
- W1975812457 cites W2114532627 @default.
- W1975812457 cites W2132937950 @default.
- W1975812457 cites W2147259607 @default.
- W1975812457 cites W2164824078 @default.
- W1975812457 cites W2168490892 @default.
- W1975812457 cites W2750358560 @default.
- W1975812457 cites W4245625679 @default.
- W1975812457 cites W4247571153 @default.
- W1975812457 doi "https://doi.org/10.1016/j.ijcard.2005.02.034" @default.
- W1975812457 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16337497" @default.
- W1975812457 hasPublicationYear "2006" @default.
- W1975812457 type Work @default.
- W1975812457 sameAs 1975812457 @default.
- W1975812457 citedByCount "27" @default.
- W1975812457 countsByYear W19758124572013 @default.
- W1975812457 countsByYear W19758124572014 @default.
- W1975812457 countsByYear W19758124572017 @default.
- W1975812457 countsByYear W19758124572018 @default.
- W1975812457 countsByYear W19758124572019 @default.
- W1975812457 countsByYear W19758124572020 @default.
- W1975812457 countsByYear W19758124572023 @default.
- W1975812457 crossrefType "journal-article" @default.
- W1975812457 hasAuthorship W1975812457A5005637906 @default.
- W1975812457 hasAuthorship W1975812457A5010606352 @default.
- W1975812457 hasAuthorship W1975812457A5024822994 @default.
- W1975812457 hasAuthorship W1975812457A5025580504 @default.
- W1975812457 hasAuthorship W1975812457A5039586274 @default.
- W1975812457 hasAuthorship W1975812457A5043160800 @default.
- W1975812457 hasAuthorship W1975812457A5052840744 @default.
- W1975812457 hasAuthorship W1975812457A5053545087 @default.
- W1975812457 hasAuthorship W1975812457A5058553514 @default.
- W1975812457 hasAuthorship W1975812457A5087927550 @default.
- W1975812457 hasConcept C126322002 @default.
- W1975812457 hasConcept C144469398 @default.
- W1975812457 hasConcept C164705383 @default.
- W1975812457 hasConcept C2776291336 @default.
- W1975812457 hasConcept C2777385415 @default.
- W1975812457 hasConcept C2778902376 @default.
- W1975812457 hasConcept C2780040984 @default.
- W1975812457 hasConcept C2780400711 @default.
- W1975812457 hasConcept C36036425 @default.
- W1975812457 hasConcept C36880943 @default.
- W1975812457 hasConcept C45393284 @default.
- W1975812457 hasConcept C500558357 @default.
- W1975812457 hasConcept C71924100 @default.
- W1975812457 hasConcept C8880881 @default.
- W1975812457 hasConceptScore W1975812457C126322002 @default.
- W1975812457 hasConceptScore W1975812457C144469398 @default.
- W1975812457 hasConceptScore W1975812457C164705383 @default.
- W1975812457 hasConceptScore W1975812457C2776291336 @default.
- W1975812457 hasConceptScore W1975812457C2777385415 @default.
- W1975812457 hasConceptScore W1975812457C2778902376 @default.
- W1975812457 hasConceptScore W1975812457C2780040984 @default.
- W1975812457 hasConceptScore W1975812457C2780400711 @default.
- W1975812457 hasConceptScore W1975812457C36036425 @default.
- W1975812457 hasConceptScore W1975812457C36880943 @default.
- W1975812457 hasConceptScore W1975812457C45393284 @default.
- W1975812457 hasConceptScore W1975812457C500558357 @default.