Matches in SemOpenAlex for { <https://semopenalex.org/work/W1975822054> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W1975822054 endingPage "135" @default.
- W1975822054 startingPage "122" @default.
- W1975822054 abstract "Background: Clinical trials are widely used to approve the efficacy and discover adverse reactions of new drugs. However, there has been much concern about the unjustified exclusion of the older adults in clinical trials. The purpose of this study was to assess ageism in clinical trials and to find solution to any discovered discrimination. Methods: An online questionnaire was completed by 1,650 experts including doctors, pharmaceutical staff, and contract research organization members. An offline inquiry was conducted by 250 experienced professors from a single tertiary hospital and other allied professions. The questions covered the current state of elderly participation, possible reasons for under-representation, and plans for its solution. Results: Among 1,900 subjects, 246 (12.9%) individuals completed the survey. We excluded the six subjects who did not answer more than 10 questions, and analyzed the remaining 240 respondents. They agreed that there are tendencies to exclude the aged from clinical trials (69.2%), and that under-representation would cause difficulties for doctors and geriatric patients. Most people (84.6%) thought that treating older adults with the results from trials which exclude aged participants is inappropriate. Because respondents had difficulties explaining the trial process and obtaining informed consent, they thought establishing a geriatric clinical trial team would be highly effective. Experts also believed that financial inducements and legal regulations are required to increase elderly enrollment. Conclusion: Because the elderly have a unique physiology, the participation of older adults in clinical research is indispensable for verifying efficacy and determining potential adverse reactions. Consequently, clinical research professionals should be concerned about the participation of older subjects, and the authorities must begin to care about age discrimination in research fields." @default.
- W1975822054 created "2016-06-24" @default.
- W1975822054 creator A5005301507 @default.
- W1975822054 creator A5012153148 @default.
- W1975822054 creator A5028102824 @default.
- W1975822054 creator A5042636483 @default.
- W1975822054 creator A5054187738 @default.
- W1975822054 creator A5056069164 @default.
- W1975822054 creator A5057554500 @default.
- W1975822054 creator A5072267593 @default.
- W1975822054 creator A5086784581 @default.
- W1975822054 date "2014-09-30" @default.
- W1975822054 modified "2023-10-16" @default.
- W1975822054 title "Current State and Future Improvement of the Elderly Participation in Clinical Trials" @default.
- W1975822054 cites W1948961602 @default.
- W1975822054 cites W1974689215 @default.
- W1975822054 cites W1981738477 @default.
- W1975822054 cites W2031162411 @default.
- W1975822054 cites W2033854183 @default.
- W1975822054 cites W2043990618 @default.
- W1975822054 cites W2046289412 @default.
- W1975822054 cites W2054371281 @default.
- W1975822054 cites W2074382219 @default.
- W1975822054 cites W2077839965 @default.
- W1975822054 cites W2111945961 @default.
- W1975822054 cites W2115598517 @default.
- W1975822054 cites W2121859696 @default.
- W1975822054 cites W2123927174 @default.
- W1975822054 cites W2154317905 @default.
- W1975822054 cites W2162992827 @default.
- W1975822054 cites W2163480476 @default.
- W1975822054 cites W2168272173 @default.
- W1975822054 cites W2323458614 @default.
- W1975822054 cites W2622205469 @default.
- W1975822054 doi "https://doi.org/10.4235/jkgs.2014.18.3.122" @default.
- W1975822054 hasPublicationYear "2014" @default.
- W1975822054 type Work @default.
- W1975822054 sameAs 1975822054 @default.
- W1975822054 citedByCount "1" @default.
- W1975822054 countsByYear W19758220542020 @default.
- W1975822054 crossrefType "journal-article" @default.
- W1975822054 hasAuthorship W1975822054A5005301507 @default.
- W1975822054 hasAuthorship W1975822054A5012153148 @default.
- W1975822054 hasAuthorship W1975822054A5028102824 @default.
- W1975822054 hasAuthorship W1975822054A5042636483 @default.
- W1975822054 hasAuthorship W1975822054A5054187738 @default.
- W1975822054 hasAuthorship W1975822054A5056069164 @default.
- W1975822054 hasAuthorship W1975822054A5057554500 @default.
- W1975822054 hasAuthorship W1975822054A5072267593 @default.
- W1975822054 hasAuthorship W1975822054A5086784581 @default.
- W1975822054 hasBestOaLocation W19758220541 @default.
- W1975822054 hasConcept C11413529 @default.
- W1975822054 hasConcept C119599485 @default.
- W1975822054 hasConcept C126322002 @default.
- W1975822054 hasConcept C127413603 @default.
- W1975822054 hasConcept C148043351 @default.
- W1975822054 hasConcept C15744967 @default.
- W1975822054 hasConcept C17744445 @default.
- W1975822054 hasConcept C41008148 @default.
- W1975822054 hasConcept C48103436 @default.
- W1975822054 hasConcept C535046627 @default.
- W1975822054 hasConcept C71924100 @default.
- W1975822054 hasConcept C74909509 @default.
- W1975822054 hasConcept C99508421 @default.
- W1975822054 hasConceptScore W1975822054C11413529 @default.
- W1975822054 hasConceptScore W1975822054C119599485 @default.
- W1975822054 hasConceptScore W1975822054C126322002 @default.
- W1975822054 hasConceptScore W1975822054C127413603 @default.
- W1975822054 hasConceptScore W1975822054C148043351 @default.
- W1975822054 hasConceptScore W1975822054C15744967 @default.
- W1975822054 hasConceptScore W1975822054C17744445 @default.
- W1975822054 hasConceptScore W1975822054C41008148 @default.
- W1975822054 hasConceptScore W1975822054C48103436 @default.
- W1975822054 hasConceptScore W1975822054C535046627 @default.
- W1975822054 hasConceptScore W1975822054C71924100 @default.
- W1975822054 hasConceptScore W1975822054C74909509 @default.
- W1975822054 hasConceptScore W1975822054C99508421 @default.
- W1975822054 hasIssue "3" @default.
- W1975822054 hasLocation W19758220541 @default.
- W1975822054 hasOpenAccess W1975822054 @default.
- W1975822054 hasPrimaryLocation W19758220541 @default.
- W1975822054 hasRelatedWork W2219524995 @default.
- W1975822054 hasRelatedWork W2619803348 @default.
- W1975822054 hasRelatedWork W2748952813 @default.
- W1975822054 hasRelatedWork W2899084033 @default.
- W1975822054 hasRelatedWork W2911551448 @default.
- W1975822054 hasRelatedWork W3003813100 @default.
- W1975822054 hasRelatedWork W3143641795 @default.
- W1975822054 hasRelatedWork W4292185485 @default.
- W1975822054 hasRelatedWork W4292290903 @default.
- W1975822054 hasRelatedWork W4365515582 @default.
- W1975822054 hasVolume "18" @default.
- W1975822054 isParatext "false" @default.
- W1975822054 isRetracted "false" @default.
- W1975822054 magId "1975822054" @default.
- W1975822054 workType "article" @default.