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- W1975848200 abstract "The activation and differentiation of CD8 T cells is a necessary first step that endows these cells with the phenotypic and functional properties required for the control of intracellular pathogens. The induction of the CD8 T cell responses typically results in the development of a massive overall population of effector cells, comprising both highly functional but short-lived terminally differentiated cells, as well as a smaller subset of precursors that are predisposed to survive and transition into the memory T cell pool. In this review, we discuss how inflammatory cytokines and IL-2 bias the initial response towards short-lived effector generation, and also highlight the potential counterbalancing role of IL-21." @default.
- W1975848200 created "2016-06-24" @default.
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- W1975848200 date "2011-04-01" @default.
- W1975848200 modified "2023-09-25" @default.
- W1975848200 title "Cytokines and the inception of CD8 T cell responses" @default.
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- W1975848200 doi "https://doi.org/10.1016/j.it.2011.01.004" @default.
- W1975848200 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3074938" @default.
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