Matches in SemOpenAlex for { <https://semopenalex.org/work/W1975857636> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W1975857636 endingPage "253" @default.
- W1975857636 startingPage "247" @default.
- W1975857636 abstract "Interleukin‐6 (IL‐6) is a multifunctional cytokine that plays important roles in the immune system, hematopoiesis, and acute phase reactions. Transforming growth factor‐β (TGF‐β) also has pleiotropy including the production of acute phase proteins in hepatocytes. To elucidate the cross‐talk between IL‐6 and TGF‐β signaling pathways in hepatic cells, we investigated the effects of TGF‐β on IL‐6‐induced signal transducer and activator of transcription‐3 (STAT3) activation in a human hepatoma cell line, Hep3B. IL‐6‐induced activation of STAT3 activity and STAT3‐mediated gene expression were augmented by TGF‐β in Hep3B cells. We provide evidence that these activities were due to physical interactions between STAT3 and Sma‐ and MAD‐related protein‐3, bridged by p300. These results demonstrate a molecular mechanism of a cross‐talk between STAT3 and TGF‐β signaling pathways in hepatocytes." @default.
- W1975857636 created "2016-06-24" @default.
- W1975857636 creator A5016798596 @default.
- W1975857636 creator A5018427930 @default.
- W1975857636 creator A5027919674 @default.
- W1975857636 creator A5051009186 @default.
- W1975857636 creator A5090298420 @default.
- W1975857636 date "2001-03-12" @default.
- W1975857636 modified "2023-09-25" @default.
- W1975857636 title "Cross-talk between IL-6 and TGF-β signaling in hepatoma cells" @default.
- W1975857636 cites W1479925198 @default.
- W1975857636 cites W1496109170 @default.
- W1975857636 cites W1663371441 @default.
- W1975857636 cites W1964815717 @default.
- W1975857636 cites W1965425054 @default.
- W1975857636 cites W1966687443 @default.
- W1975857636 cites W1970727241 @default.
- W1975857636 cites W1977681992 @default.
- W1975857636 cites W1979787580 @default.
- W1975857636 cites W1997487091 @default.
- W1975857636 cites W2003798179 @default.
- W1975857636 cites W2006008590 @default.
- W1975857636 cites W2008577129 @default.
- W1975857636 cites W2020890089 @default.
- W1975857636 cites W2029275361 @default.
- W1975857636 cites W2030865745 @default.
- W1975857636 cites W2042218061 @default.
- W1975857636 cites W2072482570 @default.
- W1975857636 cites W2085451664 @default.
- W1975857636 cites W2119282745 @default.
- W1975857636 cites W2131815302 @default.
- W1975857636 cites W2133193835 @default.
- W1975857636 cites W2154746915 @default.
- W1975857636 doi "https://doi.org/10.1016/s0014-5793(01)02258-x" @default.
- W1975857636 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11257503" @default.
- W1975857636 hasPublicationYear "2001" @default.
- W1975857636 type Work @default.
- W1975857636 sameAs 1975857636 @default.
- W1975857636 citedByCount "64" @default.
- W1975857636 countsByYear W19758576362012 @default.
- W1975857636 countsByYear W19758576362013 @default.
- W1975857636 countsByYear W19758576362014 @default.
- W1975857636 countsByYear W19758576362015 @default.
- W1975857636 countsByYear W19758576362016 @default.
- W1975857636 countsByYear W19758576362017 @default.
- W1975857636 countsByYear W19758576362018 @default.
- W1975857636 countsByYear W19758576362019 @default.
- W1975857636 countsByYear W19758576362020 @default.
- W1975857636 countsByYear W19758576362021 @default.
- W1975857636 countsByYear W19758576362022 @default.
- W1975857636 countsByYear W19758576362023 @default.
- W1975857636 crossrefType "journal-article" @default.
- W1975857636 hasAuthorship W1975857636A5016798596 @default.
- W1975857636 hasAuthorship W1975857636A5018427930 @default.
- W1975857636 hasAuthorship W1975857636A5027919674 @default.
- W1975857636 hasAuthorship W1975857636A5051009186 @default.
- W1975857636 hasAuthorship W1975857636A5090298420 @default.
- W1975857636 hasBestOaLocation W19758576361 @default.
- W1975857636 hasConcept C118131993 @default.
- W1975857636 hasConcept C171958077 @default.
- W1975857636 hasConcept C185592680 @default.
- W1975857636 hasConcept C203014093 @default.
- W1975857636 hasConcept C2778277574 @default.
- W1975857636 hasConcept C2778690821 @default.
- W1975857636 hasConcept C2778923194 @default.
- W1975857636 hasConcept C62478195 @default.
- W1975857636 hasConcept C86803240 @default.
- W1975857636 hasConcept C95444343 @default.
- W1975857636 hasConceptScore W1975857636C118131993 @default.
- W1975857636 hasConceptScore W1975857636C171958077 @default.
- W1975857636 hasConceptScore W1975857636C185592680 @default.
- W1975857636 hasConceptScore W1975857636C203014093 @default.
- W1975857636 hasConceptScore W1975857636C2778277574 @default.
- W1975857636 hasConceptScore W1975857636C2778690821 @default.
- W1975857636 hasConceptScore W1975857636C2778923194 @default.
- W1975857636 hasConceptScore W1975857636C62478195 @default.
- W1975857636 hasConceptScore W1975857636C86803240 @default.
- W1975857636 hasConceptScore W1975857636C95444343 @default.
- W1975857636 hasIssue "3" @default.
- W1975857636 hasLocation W19758576361 @default.
- W1975857636 hasLocation W19758576362 @default.
- W1975857636 hasOpenAccess W1975857636 @default.
- W1975857636 hasPrimaryLocation W19758576361 @default.
- W1975857636 hasRelatedWork W104615584 @default.
- W1975857636 hasRelatedWork W1986625462 @default.
- W1975857636 hasRelatedWork W1996172186 @default.
- W1975857636 hasRelatedWork W1998149586 @default.
- W1975857636 hasRelatedWork W2021469201 @default.
- W1975857636 hasRelatedWork W2023281530 @default.
- W1975857636 hasRelatedWork W2143855590 @default.
- W1975857636 hasRelatedWork W2926512122 @default.
- W1975857636 hasRelatedWork W3029461162 @default.
- W1975857636 hasRelatedWork W2424898401 @default.
- W1975857636 hasVolume "492" @default.
- W1975857636 isParatext "false" @default.
- W1975857636 isRetracted "false" @default.
- W1975857636 magId "1975857636" @default.
- W1975857636 workType "article" @default.