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• W1975869000 abstract "Évaluer la couverture vaccinale chez les grands prématurés de moins de 33 semaines d’aménorrhée (SA) à l’âge de 6 et 24 mois. L’étude a concerné 87 enfants issus d’une cohorte régionale, nés en 2000 avant le terme de 33 SA. L’âge gestationnel moyen était de 30 SA (25–32 SA) et le poids moyen était de 1400 g (550–2550 g). Le programme vaccinal avait débuté tardivement, le plus souvent (63 %) par les valences DTPCoqHib (diphtérie, tétanos, poliomyélite, coqueluche, haemophilus influenzae), en moyenne après le 4e mois. Moins de la moitié des enfants (45 %) avait reçu 3 doses à 6 mois. À 2 ans, 99 % des enfants avaient reçu 3 doses mais seulement 83 % avaient reçu 4 doses. La vaccination ROR (rougeole, oreillons, rubéole) avait été effectuée en moyenne après l’âge de 15 mois et 95 % des enfants avaient reçu une dose à 2 ans. La plupart des enfants (94 %) avaient reçu le BCG à 2 ans, en moyenne vers l’âge de 7 mois. Pour l’hépatite B, 47 % avaient reçu au moins 1 dose à 2 ans, mais seuls 31 % des enfants avaient reçu 2 doses et un rappel à 2 ans. La 1re injection vaccinale n’avait eu lieu à l’hôpital que pour 15 % des enfants. Ce retard persistait au cours des 2 premières années, et augmentait la période de vulnérabilité de ces enfants. Seuls 28 % des enfants prématurés satisfaisaient aux recommandations françaises pour les valences DTPCoqHib, ROR et Hépatite B à l’âge de 2 ans. L’initiation de la vaccination se met en place avec retard chez l’enfant né prématuré. La réalité est loin des objectifs collectifs à l’âge de 2 ans. La couverture pour la coqueluche est préoccupante pendant la 1re année. L’initiation de la vaccination chez les grands prématurés avant le retour à domicile devra être encouragée pour les enfants hospitalisés plus de 2 mois et la vaccination de l’entourage des enfants prématurés proposée à l’occasion d’un rappel vaccinal. There are few data examining the vaccine practices for 0- to 24-month-old premature infants born before 33 GW. The aim of the study was to examine the vaccine coverage in this population according to the French schedule at 6 and 24 months. Eighty-seven infants were included in this regional prospective study. The immunization program began late and was initialized principally with DTPCoqHib (63%), usually after the 4th month. Fewer than one infant out of two (45%) had received three doses by 6 months of age. At 2 years of age, the coverage was 99% at 3 doses and decreased to 83% for 4 doses. For the MMR vaccine, the average age of administration was after 15 months, and 95% of infants had received one dose of MMR at 2 years of age. BCG coverage at 2 years of age was 94%, administered on average at 7 months. Forty-seven percent of the infants had received at least one dose of hepatitis B vaccine before 2 years of age, but only 31% had received two doses and a booster at 2 years of age. The adaptation of vaccination practices basically concerns the initial date of vaccination, but the immunization calendar is not recovered at 2 years of age. This should be taken into account for pertussis disease prevention in these young infants during the first 6 months of life, increasing the susceptibility period for this infectious disease. The vaccine practices do not follow the postnatal chronological age of the premature baby according to the schedule recommended for full-term infants and vaccination is begun late. Based on the CSHPF vaccination recommendations, nearly 7 premature infants out of 10 have an incomplete immunization status for DTPCoqHib, hepatitis B, and ROR at 2 years of age. According to the pertussis coverage observed in premature infants, the new recommendations on vaccination of the newborn's care giver and family should be completed before the infant's discharge from the hospital using a new acellular vaccine for adult immunization. The initiation of an immunization program during hospitalization would be beneficial for premature babies still hospitalized after 2 months of age." @default.
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• W1975869000 date "2009-12-01" @default.
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• W1975869000 title "Couverture vaccinale des grands prématurés à 6 mois et à 2 ans : étude pilote" @default.
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• W1975869000 doi "https://doi.org/10.1016/j.arcped.2009.09.009" @default.
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