Matches in SemOpenAlex for { <https://semopenalex.org/work/W1975882014> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W1975882014 endingPage "389" @default.
- W1975882014 startingPage "381" @default.
- W1975882014 abstract "The distribution of anionic (negatively charged) groups on the surface of retinal pigment epithelial cells (RPE), rod photoreceptor cells (RP) and discarded rod outer segments (R0S) was studied by labeling these groups with cationic ferritin (CF) at different pH values. In normal neonatal rats, characteristic CF binding patterns were observed on the RPE cell surface at pH values ranging from 1.8-7.2. Similar distributions were seen on the surface of RPE cells from RCS-p+ rats with inherited retinal degeneration. Treatment of RPE cells from normal neonates with several different degradative enzyme preparations prior to CF labeling, did not alter the density or distribution of CF molecules at any of the pH values tested. In normal adult rats, CF binding to RPE cells was essentially similar to that observed in neonates. In RP cells, heavy CF labeling at pH 1.8 was seen on the surface of the inner and outer segments and connecting cilium. CF labeling patterns on discarded R0S undergoing phagocytosis were similar to those on RPE cells at all pH values except pH 5.5. The findings indicate that anionic sites are present on the surface of RPE and RP cells and on discarded R0S undergoing phagocytosis. There is no evidence that such sites are involved in the phagocytic defect characteristic of RCS-p+ rats. Adult-like patterns of anionic sites on RPE cells appear early in postnatal development; their resistance to a wide range of degradative enzymes suggests that the carbohydrates or proteins containing these anionic moieties are organized in a complex fashion in the RPE cell surface." @default.
- W1975882014 created "2016-06-24" @default.
- W1975882014 creator A5012182252 @default.
- W1975882014 creator A5068599592 @default.
- W1975882014 creator A5077741699 @default.
- W1975882014 date "1981-01-01" @default.
- W1975882014 modified "2023-09-26" @default.
- W1975882014 title "Distribution of anionic sites on the surface of retinal pigment epithelial and rod photo-receptor cells" @default.
- W1975882014 cites W1833226440 @default.
- W1975882014 cites W1963591622 @default.
- W1975882014 cites W1964485359 @default.
- W1975882014 cites W1980741458 @default.
- W1975882014 cites W1996428478 @default.
- W1975882014 cites W2033823572 @default.
- W1975882014 cites W2038505057 @default.
- W1975882014 cites W2059669195 @default.
- W1975882014 cites W2083062636 @default.
- W1975882014 cites W2109401564 @default.
- W1975882014 cites W2118727571 @default.
- W1975882014 cites W2126577146 @default.
- W1975882014 cites W2270523344 @default.
- W1975882014 cites W2283717907 @default.
- W1975882014 cites W2399961868 @default.
- W1975882014 doi "https://doi.org/10.3109/02713688109019975" @default.
- W1975882014 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7318491" @default.
- W1975882014 hasPublicationYear "1981" @default.
- W1975882014 type Work @default.
- W1975882014 sameAs 1975882014 @default.
- W1975882014 citedByCount "7" @default.
- W1975882014 countsByYear W19758820142022 @default.
- W1975882014 crossrefType "journal-article" @default.
- W1975882014 hasAuthorship W1975882014A5012182252 @default.
- W1975882014 hasAuthorship W1975882014A5068599592 @default.
- W1975882014 hasAuthorship W1975882014A5077741699 @default.
- W1975882014 hasConcept C12554922 @default.
- W1975882014 hasConcept C1491633281 @default.
- W1975882014 hasConcept C153911025 @default.
- W1975882014 hasConcept C160448771 @default.
- W1975882014 hasConcept C169760540 @default.
- W1975882014 hasConcept C170493617 @default.
- W1975882014 hasConcept C178790620 @default.
- W1975882014 hasConcept C185592680 @default.
- W1975882014 hasConcept C2777093970 @default.
- W1975882014 hasConcept C2778024200 @default.
- W1975882014 hasConcept C2780827179 @default.
- W1975882014 hasConcept C55493867 @default.
- W1975882014 hasConcept C64584667 @default.
- W1975882014 hasConcept C86803240 @default.
- W1975882014 hasConcept C95444343 @default.
- W1975882014 hasConceptScore W1975882014C12554922 @default.
- W1975882014 hasConceptScore W1975882014C1491633281 @default.
- W1975882014 hasConceptScore W1975882014C153911025 @default.
- W1975882014 hasConceptScore W1975882014C160448771 @default.
- W1975882014 hasConceptScore W1975882014C169760540 @default.
- W1975882014 hasConceptScore W1975882014C170493617 @default.
- W1975882014 hasConceptScore W1975882014C178790620 @default.
- W1975882014 hasConceptScore W1975882014C185592680 @default.
- W1975882014 hasConceptScore W1975882014C2777093970 @default.
- W1975882014 hasConceptScore W1975882014C2778024200 @default.
- W1975882014 hasConceptScore W1975882014C2780827179 @default.
- W1975882014 hasConceptScore W1975882014C55493867 @default.
- W1975882014 hasConceptScore W1975882014C64584667 @default.
- W1975882014 hasConceptScore W1975882014C86803240 @default.
- W1975882014 hasConceptScore W1975882014C95444343 @default.
- W1975882014 hasIssue "7" @default.
- W1975882014 hasLocation W19758820141 @default.
- W1975882014 hasLocation W19758820142 @default.
- W1975882014 hasOpenAccess W1975882014 @default.
- W1975882014 hasPrimaryLocation W19758820141 @default.
- W1975882014 hasRelatedWork W2026122014 @default.
- W1975882014 hasRelatedWork W2059775955 @default.
- W1975882014 hasRelatedWork W2071394605 @default.
- W1975882014 hasRelatedWork W2138842146 @default.
- W1975882014 hasRelatedWork W2470975092 @default.
- W1975882014 hasRelatedWork W2499532004 @default.
- W1975882014 hasRelatedWork W2617421506 @default.
- W1975882014 hasRelatedWork W2949205313 @default.
- W1975882014 hasRelatedWork W820708669 @default.
- W1975882014 hasRelatedWork W910497588 @default.
- W1975882014 hasVolume "1" @default.
- W1975882014 isParatext "false" @default.
- W1975882014 isRetracted "false" @default.
- W1975882014 magId "1975882014" @default.
- W1975882014 workType "article" @default.