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• W1975909743 abstract "Décrire les médicaments utilisés dans le traitement hormonal (hormonothérapie) du cancer de la prostate. Recherche bibliographique à partir de la base de données Medline (National Library of Medicine, outil PubMed), des sites de l’HAS et de l’ANSM. La recherche était centrée sur les caractéristiques, le mode d’action, l’efficacité et les effets secondaires des différentes classes de médicaments concernées. Les analogues de la LHRH et les anti-androgènes demeurent la pierre angulaire dans la prise en charge du cancer de la prostate pour les stades localement évolués, métastatiques ou en cas de récidive de la maladie. Des nouvelles classes de médicaments ont émergé récemment (inhibiteur de la synthèse des androgènes, nouveaux anti-androgènes) et ont permis de repousser les limites de l’hormonorésistance et de définir le concept de résistance à la castration. Le traitement hormonal du cancer de la prostate s’est enrichi de nouvelles classes thérapeutiques qui vont changer la prise en charge du cancer de la prostate dans les prochaines années où l’urologue doit prendre toute sa place. To describe drugs used in the hormonal treatment (hormonotherapy) of prostate cancer. Bibliographical search was performed from the database Medline (National Library of Medicine, PubMed) and websites of the HAS and the ANSM. The search was focused on the characteristics, the mode of action, the efficiency and the side effects of the various drugs concerned. LHRH analogs and the antiandrogens remain the cornerstone in the treatment of locally advanced and metastatic prostate cancer. New therapeutic classes emerged recently (inhibitor of the synthesis of the androgen, the new antiandrogens) and allowed to grow again the limits of the hormone resistance and define the concept castration-resistant prostate cancer. The hormonal treatment of the prostate cancer grew rich of new therapeutic classes which are going to change the medical care of the prostate cancer in the coming years and the urologist must play its full part." @default.
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• W1975909743 date "2013-11-01" @default.
• W1975909743 modified "2023-10-16" @default.
• W1975909743 title "Le traitement hormonal du cancer de la prostate" @default.
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• W1975909743 doi "https://doi.org/10.1016/j.purol.2013.08.325" @default.
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