FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1975960468> ?p ?o ?g. }

• W1975960468 endingPage "262" @default.
• W1975960468 startingPage "259" @default.
• W1975960468 abstract "The stem bark of Mammea africana is widely distributed in tropical Africa and commonly used in traditional medicine. This study aims to identify the active compound in Mammea africana and to evaluate its antimicrobial and antiproliferative activity. Methanol extract from the bark of the Mammea africana was separated by liquid–liquid extraction, followed by open column chromatography. A principal antimicrobial compound was purified by high performance liquid chromatography (HPLC) and its structure was elucidated by nuclear magnetic resonance spectroscopy (NMR) and mass spectrometry (MS). The antibacterial activity of the purified compound was determined using the broth microdilution method against 7 common pathogenic bacteria. The compound was also evaluated for cytotoxicity by cell proliferation assay (MTS) using the mouse embryonic fibroblast cell line NIH 3T3 and the non-small cell lung cancer cell line A549. The purified active compound was determined to be mammea A/AA and was found to be highly active against Campylobacter jejuni (MIC=0.5 μg/ml), Streptococcus pneumoniae (MIC=0.25 μg/ml), and Clostridium difficile (MIC=0.25 μg/ml). The compound exhibited significant antiproliferative activities against both NIH 3T3 and A549 cell lines. Mammea A/AA isolated from Mammea africana exerts specific inhibitory activity against Campylobacter jejuni, Streptococcus pneumoniae, and Campylobacter difficile. Mammea A/AA was also found to exhibit significant cytotoxicity against both cancer and normal cell lines." @default.
• W1975960468 created "2016-06-24" @default.
• W1975960468 creator A5001408219 @default.
• W1975960468 creator A5005725890 @default.
• W1975960468 creator A5027891544 @default.
• W1975960468 creator A5058675816 @default.
• W1975960468 creator A5068934076 @default.
• W1975960468 date "2013-05-01" @default.
• W1975960468 modified "2023-10-14" @default.
• W1975960468 title "Antibacterial and cytotoxic activity of isoprenylated coumarin mammea A/AA isolated from Mammea africana" @default.
• W1975960468 cites W1999761519 @default.
• W1975960468 cites W2016023105 @default.
• W1975960468 cites W2064794566 @default.
• W1975960468 cites W2074450709 @default.
• W1975960468 cites W2107508284 @default.
• W1975960468 cites W2117423935 @default.
• W1975960468 cites W2126510656 @default.
• W1975960468 cites W2139469603 @default.
• W1975960468 cites W2151890502 @default.
• W1975960468 cites W2154400468 @default.
• W1975960468 cites W2165460519 @default.
• W1975960468 cites W2166660180 @default.
• W1975960468 cites W2168163462 @default.
• W1975960468 cites W2336287850 @default.
• W1975960468 doi "https://doi.org/10.1016/j.jep.2013.02.026" @default.
• W1975960468 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23466248" @default.
• W1975960468 hasPublicationYear "2013" @default.
• W1975960468 type Work @default.
• W1975960468 sameAs 1975960468 @default.
• W1975960468 citedByCount "38" @default.
• W1975960468 countsByYear W19759604682013 @default.
• W1975960468 countsByYear W19759604682014 @default.
• W1975960468 countsByYear W19759604682015 @default.
• W1975960468 countsByYear W19759604682016 @default.
• W1975960468 countsByYear W19759604682017 @default.
• W1975960468 countsByYear W19759604682018 @default.
• W1975960468 countsByYear W19759604682019 @default.
• W1975960468 countsByYear W19759604682020 @default.
• W1975960468 countsByYear W19759604682021 @default.
• W1975960468 countsByYear W19759604682022 @default.
• W1975960468 countsByYear W19759604682023 @default.
• W1975960468 crossrefType "journal-article" @default.
• W1975960468 hasAuthorship W1975960468A5001408219 @default.
• W1975960468 hasAuthorship W1975960468A5005725890 @default.
• W1975960468 hasAuthorship W1975960468A5027891544 @default.
• W1975960468 hasAuthorship W1975960468A5058675816 @default.
• W1975960468 hasAuthorship W1975960468A5068934076 @default.
• W1975960468 hasConcept C109316439 @default.
• W1975960468 hasConcept C133446333 @default.
• W1975960468 hasConcept C176947019 @default.
• W1975960468 hasConcept C185592680 @default.
• W1975960468 hasConcept C18903297 @default.
• W1975960468 hasConcept C202751555 @default.
• W1975960468 hasConcept C2778004101 @default.
• W1975960468 hasConcept C2780104969 @default.
• W1975960468 hasConcept C2780950330 @default.
• W1975960468 hasConcept C2781253189 @default.
• W1975960468 hasConcept C2781464872 @default.
• W1975960468 hasConcept C4937899 @default.
• W1975960468 hasConcept C501593827 @default.
• W1975960468 hasConcept C523546767 @default.
• W1975960468 hasConcept C54355233 @default.
• W1975960468 hasConcept C55493867 @default.
• W1975960468 hasConcept C556039675 @default.
• W1975960468 hasConcept C70899900 @default.
• W1975960468 hasConcept C71924100 @default.
• W1975960468 hasConcept C86803240 @default.
• W1975960468 hasConcept C89423630 @default.
• W1975960468 hasConceptScore W1975960468C109316439 @default.
• W1975960468 hasConceptScore W1975960468C133446333 @default.
• W1975960468 hasConceptScore W1975960468C176947019 @default.
• W1975960468 hasConceptScore W1975960468C185592680 @default.
• W1975960468 hasConceptScore W1975960468C18903297 @default.
• W1975960468 hasConceptScore W1975960468C202751555 @default.
• W1975960468 hasConceptScore W1975960468C2778004101 @default.
• W1975960468 hasConceptScore W1975960468C2780104969 @default.
• W1975960468 hasConceptScore W1975960468C2780950330 @default.
• W1975960468 hasConceptScore W1975960468C2781253189 @default.
• W1975960468 hasConceptScore W1975960468C2781464872 @default.
• W1975960468 hasConceptScore W1975960468C4937899 @default.
• W1975960468 hasConceptScore W1975960468C501593827 @default.
• W1975960468 hasConceptScore W1975960468C523546767 @default.
• W1975960468 hasConceptScore W1975960468C54355233 @default.
• W1975960468 hasConceptScore W1975960468C55493867 @default.
• W1975960468 hasConceptScore W1975960468C556039675 @default.
• W1975960468 hasConceptScore W1975960468C70899900 @default.
• W1975960468 hasConceptScore W1975960468C71924100 @default.
• W1975960468 hasConceptScore W1975960468C86803240 @default.
• W1975960468 hasConceptScore W1975960468C89423630 @default.
• W1975960468 hasIssue "1" @default.
• W1975960468 hasLocation W19759604681 @default.
• W1975960468 hasLocation W19759604682 @default.
• W1975960468 hasOpenAccess W1975960468 @default.
• W1975960468 hasPrimaryLocation W19759604681 @default.
• W1975960468 hasRelatedWork W1555208341 @default.
• W1975960468 hasRelatedWork W2049060805 @default.
• W1975960468 hasRelatedWork W2172901652 @default.
• W1975960468 hasRelatedWork W2361473255 @default.

• next