Matches in SemOpenAlex for { <https://semopenalex.org/work/W1975970371> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W1975970371 endingPage "51" @default.
- W1975970371 startingPage "44" @default.
- W1975970371 abstract "Aluminum-containing adjuvants (alum) continue to be the most widely used adjuvants. It is common knowledge that these adjuvants predominantly induce humoral immunity, but some reports also describe their role combined with IL-12 in the induction of a Th1 immune response. In this study we want to investigate if alum could be an adjuvant to be used as a component of a therapeutic vaccine that require the generation of cell-mediated immunity. To demonstrate this concept we selected the human papillomavirus (HPV) 16-transformed mouse TC-1 cells as model and the fusion protein LALF32-51-E7 as antigen. Our results suggest that LALF32-51-E7 combined with aluminum hydroxide adjuvant promotes a Th1 immune response and consequently an anti-tumor response in the TC-1 tumor model. These results could have important application in future clinical trials in women with low grade squamous intraepithelial neoplasia." @default.
- W1975970371 created "2016-06-24" @default.
- W1975970371 creator A5008420464 @default.
- W1975970371 creator A5021484352 @default.
- W1975970371 creator A5024386319 @default.
- W1975970371 creator A5035600306 @default.
- W1975970371 creator A5045572356 @default.
- W1975970371 creator A5059856470 @default.
- W1975970371 creator A5069446216 @default.
- W1975970371 creator A5086008811 @default.
- W1975970371 creator A5091695518 @default.
- W1975970371 creator A5037286723 @default.
- W1975970371 date "2016-03-01" @default.
- W1975970371 modified "2023-10-18" @default.
- W1975970371 title "The LALF32-51 peptide as component of HPV therapeutic vaccine circumvents the alum-mediated inhibition of IL-12 and promotes a Th1 response" @default.
- W1975970371 cites W1548525574 @default.
- W1975970371 cites W1597089068 @default.
- W1975970371 cites W1978146796 @default.
- W1975970371 cites W2007265276 @default.
- W1975970371 cites W2009219530 @default.
- W1975970371 cites W2036196494 @default.
- W1975970371 cites W2044197227 @default.
- W1975970371 cites W2054114227 @default.
- W1975970371 cites W2062078150 @default.
- W1975970371 cites W2086929314 @default.
- W1975970371 cites W2103928621 @default.
- W1975970371 cites W2140649712 @default.
- W1975970371 cites W2160116807 @default.
- W1975970371 cites W2160436685 @default.
- W1975970371 doi "https://doi.org/10.1016/j.jocit.2015.01.001" @default.
- W1975970371 hasPublicationYear "2016" @default.
- W1975970371 type Work @default.
- W1975970371 sameAs 1975970371 @default.
- W1975970371 citedByCount "5" @default.
- W1975970371 countsByYear W19759703712017 @default.
- W1975970371 countsByYear W19759703712018 @default.
- W1975970371 countsByYear W19759703712019 @default.
- W1975970371 countsByYear W19759703712021 @default.
- W1975970371 crossrefType "journal-article" @default.
- W1975970371 hasAuthorship W1975970371A5008420464 @default.
- W1975970371 hasAuthorship W1975970371A5021484352 @default.
- W1975970371 hasAuthorship W1975970371A5024386319 @default.
- W1975970371 hasAuthorship W1975970371A5035600306 @default.
- W1975970371 hasAuthorship W1975970371A5037286723 @default.
- W1975970371 hasAuthorship W1975970371A5045572356 @default.
- W1975970371 hasAuthorship W1975970371A5059856470 @default.
- W1975970371 hasAuthorship W1975970371A5069446216 @default.
- W1975970371 hasAuthorship W1975970371A5086008811 @default.
- W1975970371 hasAuthorship W1975970371A5091695518 @default.
- W1975970371 hasBestOaLocation W19759703711 @default.
- W1975970371 hasConcept C147483822 @default.
- W1975970371 hasConcept C178790620 @default.
- W1975970371 hasConcept C185592680 @default.
- W1975970371 hasConcept C203014093 @default.
- W1975970371 hasConcept C2776548049 @default.
- W1975970371 hasConcept C2777863537 @default.
- W1975970371 hasConcept C2779341262 @default.
- W1975970371 hasConcept C2780924562 @default.
- W1975970371 hasConcept C3018913218 @default.
- W1975970371 hasConcept C71924100 @default.
- W1975970371 hasConcept C86803240 @default.
- W1975970371 hasConcept C8891405 @default.
- W1975970371 hasConceptScore W1975970371C147483822 @default.
- W1975970371 hasConceptScore W1975970371C178790620 @default.
- W1975970371 hasConceptScore W1975970371C185592680 @default.
- W1975970371 hasConceptScore W1975970371C203014093 @default.
- W1975970371 hasConceptScore W1975970371C2776548049 @default.
- W1975970371 hasConceptScore W1975970371C2777863537 @default.
- W1975970371 hasConceptScore W1975970371C2779341262 @default.
- W1975970371 hasConceptScore W1975970371C2780924562 @default.
- W1975970371 hasConceptScore W1975970371C3018913218 @default.
- W1975970371 hasConceptScore W1975970371C71924100 @default.
- W1975970371 hasConceptScore W1975970371C86803240 @default.
- W1975970371 hasConceptScore W1975970371C8891405 @default.
- W1975970371 hasIssue "1" @default.
- W1975970371 hasLocation W19759703711 @default.
- W1975970371 hasOpenAccess W1975970371 @default.
- W1975970371 hasPrimaryLocation W19759703711 @default.
- W1975970371 hasRelatedWork W1976102012 @default.
- W1975970371 hasRelatedWork W1989819860 @default.
- W1975970371 hasRelatedWork W2025057911 @default.
- W1975970371 hasRelatedWork W2027670370 @default.
- W1975970371 hasRelatedWork W2046102446 @default.
- W1975970371 hasRelatedWork W2079516589 @default.
- W1975970371 hasRelatedWork W2093242067 @default.
- W1975970371 hasRelatedWork W4213421740 @default.
- W1975970371 hasRelatedWork W4381570565 @default.
- W1975970371 hasRelatedWork W573847062 @default.
- W1975970371 hasVolume "2" @default.
- W1975970371 isParatext "false" @default.
- W1975970371 isRetracted "false" @default.
- W1975970371 magId "1975970371" @default.
- W1975970371 workType "article" @default.