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- W1975976662 abstract "While ovarian oestrogen synthesis ceases at the menopause, the ovaries and, in particular, the adrenals, synthesise androgens (androstenedione and testosterone) that may be converted into oestrogens (oestrone and oestradiol, respectively) by so-called aromatisation [ 1 Lonning P.E. Dowsett M. Powles T.J. Postmenopausal estrogen synthesis and metabolism alterations caused by aromatase inhibitors used for the treatment of breast cancer. J. Steroid Biochem. 1990; 35: 355-366 Crossref PubMed Scopus (97) Google Scholar ]. Thus, circulating androgens are taken up and converted into oestrogen in most body compartments, including benign as well as malignant breast tissue." @default.
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- W1975976662 date "2002-09-01" @default.
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- W1975976662 title "Aromatase inhibitors and inactivators for breast cancer treatment" @default.
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- W1975976662 doi "https://doi.org/10.1016/s0959-8049(02)00283-6" @default.
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