Matches in SemOpenAlex for { <https://semopenalex.org/work/W1975988897> ?p ?o ?g. }
- W1975988897 endingPage "15" @default.
- W1975988897 startingPage "8" @default.
- W1975988897 abstract "We investigated the role of connexin 43 (Cx43) hemichannels in the release of glutamate by astrocytes after hypertonic stimulus. Mechanical, osmotic and oxidative stress, and changes in the extracellular or intracellular Ca(2+) levels induce connexin hemichannels located in the plasma membrane to open and release small ions and molecules with signaling potential such as glutamate, ATP, etc. In our past studies, we primarily found that acute hypertonic stimulus induced the release of glutamate. Since glutamate release was involved with several routes, we studied its release routes by astrocytes incubated in a hypertonic media for various periods. The glutamate release was increased after hypertonic stimulus. Glutamate release in hypertonic stimulus was inhibited by gap junction or Cx43 hemichannel blockers, but not by antagonists of purinergic receptor (P2XnR), glutamate transport inhibitors, intracellular Ca(2+) blockers, and pannexin 1(Panx1) hemichannel. The results suggest that glutamate release by the Cx43 hemichannels is likely to feature in the response of cultured astrocytes to hypertonic stimulus." @default.
- W1975988897 created "2016-06-24" @default.
- W1975988897 creator A5019795468 @default.
- W1975988897 creator A5050716712 @default.
- W1975988897 creator A5052997826 @default.
- W1975988897 creator A5067802852 @default.
- W1975988897 creator A5080424321 @default.
- W1975988897 creator A5087595282 @default.
- W1975988897 creator A5091477675 @default.
- W1975988897 date "2011-05-01" @default.
- W1975988897 modified "2023-10-18" @default.
- W1975988897 title "Glutamate release through connexin 43 by cultured astrocytes in a stimulated hypertonicity model" @default.
- W1975988897 cites W114761346 @default.
- W1975988897 cites W1516426911 @default.
- W1975988897 cites W1516757462 @default.
- W1975988897 cites W1595178772 @default.
- W1975988897 cites W1629086159 @default.
- W1975988897 cites W1882376829 @default.
- W1975988897 cites W1936866440 @default.
- W1975988897 cites W1957783567 @default.
- W1975988897 cites W1966509157 @default.
- W1975988897 cites W1972107534 @default.
- W1975988897 cites W1976754780 @default.
- W1975988897 cites W1976824217 @default.
- W1975988897 cites W1977245969 @default.
- W1975988897 cites W1990386835 @default.
- W1975988897 cites W1992170663 @default.
- W1975988897 cites W1992576846 @default.
- W1975988897 cites W2001537648 @default.
- W1975988897 cites W2008277503 @default.
- W1975988897 cites W2011685558 @default.
- W1975988897 cites W2011803470 @default.
- W1975988897 cites W2016798725 @default.
- W1975988897 cites W2017203200 @default.
- W1975988897 cites W2017523469 @default.
- W1975988897 cites W2019310006 @default.
- W1975988897 cites W2021241421 @default.
- W1975988897 cites W2033803440 @default.
- W1975988897 cites W2045092834 @default.
- W1975988897 cites W2050452462 @default.
- W1975988897 cites W2050862209 @default.
- W1975988897 cites W2053682958 @default.
- W1975988897 cites W2055162787 @default.
- W1975988897 cites W2056768860 @default.
- W1975988897 cites W2057676844 @default.
- W1975988897 cites W2062887543 @default.
- W1975988897 cites W2064258187 @default.
- W1975988897 cites W2066949277 @default.
- W1975988897 cites W2068517470 @default.
- W1975988897 cites W2069913959 @default.
- W1975988897 cites W2081308583 @default.
- W1975988897 cites W2089047096 @default.
- W1975988897 cites W2091891353 @default.
- W1975988897 cites W2095231337 @default.
- W1975988897 cites W2113755529 @default.
- W1975988897 cites W2118146305 @default.
- W1975988897 cites W2118549246 @default.
- W1975988897 cites W2124017577 @default.
- W1975988897 cites W2134046709 @default.
- W1975988897 cites W2151432407 @default.
- W1975988897 cites W2161234073 @default.
- W1975988897 cites W2163252802 @default.
- W1975988897 cites W269262193 @default.
- W1975988897 cites W32980082 @default.
- W1975988897 doi "https://doi.org/10.1016/j.brainres.2011.03.056" @default.
- W1975988897 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21458428" @default.
- W1975988897 hasPublicationYear "2011" @default.
- W1975988897 type Work @default.
- W1975988897 sameAs 1975988897 @default.
- W1975988897 citedByCount "45" @default.
- W1975988897 countsByYear W19759888972012 @default.
- W1975988897 countsByYear W19759888972013 @default.
- W1975988897 countsByYear W19759888972014 @default.
- W1975988897 countsByYear W19759888972015 @default.
- W1975988897 countsByYear W19759888972016 @default.
- W1975988897 countsByYear W19759888972017 @default.
- W1975988897 countsByYear W19759888972018 @default.
- W1975988897 countsByYear W19759888972019 @default.
- W1975988897 countsByYear W19759888972020 @default.
- W1975988897 countsByYear W19759888972021 @default.
- W1975988897 crossrefType "journal-article" @default.
- W1975988897 hasAuthorship W1975988897A5019795468 @default.
- W1975988897 hasAuthorship W1975988897A5050716712 @default.
- W1975988897 hasAuthorship W1975988897A5052997826 @default.
- W1975988897 hasAuthorship W1975988897A5067802852 @default.
- W1975988897 hasAuthorship W1975988897A5080424321 @default.
- W1975988897 hasAuthorship W1975988897A5087595282 @default.
- W1975988897 hasAuthorship W1975988897A5091477675 @default.
- W1975988897 hasConcept C117277713 @default.
- W1975988897 hasConcept C12554922 @default.
- W1975988897 hasConcept C127992366 @default.
- W1975988897 hasConcept C15744967 @default.
- W1975988897 hasConcept C158157758 @default.
- W1975988897 hasConcept C169760540 @default.
- W1975988897 hasConcept C170493617 @default.
- W1975988897 hasConcept C185592680 @default.
- W1975988897 hasConcept C2779918689 @default.
- W1975988897 hasConcept C2780228694 @default.