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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1976003675> ?p ?o ?g. }

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• W1976003675 startingPage "3607" @default.
• W1976003675 abstract "The synthesis and SAR of a series of BACE-1 hydroxyethyl amine inhibitors containing substitutions on a spirocyclobutyl moiety is described. Selectivity against cathepsin D, a related aspartyl protease with potential off target toxicity, and improved microsomal stability is exemplified." @default.
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• W1976003675 date "2012-06-01" @default.
• W1976003675 modified "2023-10-15" @default.
• W1976003675 title "Structure guided P1′ modifications of HEA derived β-secretase inhibitors for the treatment of Alzheimer’s disease" @default.
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• W1976003675 doi "https://doi.org/10.1016/j.bmcl.2012.04.060" @default.
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