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- W1976020349 abstract "Abstract We have synthesized a new class of modified nucleoside, X, that could recognize adenine-thymine base pairs. They were designed to form the triple helix of A-T·X motif, where X forms hydrogen bonds to the N7 and NH2 of the far-side adenine in the major groove. Compounds 1 and 2 are a new type of triplex-forming modified nucleoside which are expected to act as DNA cleaving agents through the p-nitrophenyl group." @default.
- W1976020349 created "2016-06-24" @default.
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- W1976020349 date "1999-06-01" @default.
- W1976020349 modified "2023-10-02" @default.
- W1976020349 title "Design and synthesis of a new type of modified nucleoside for triple helix-mediated adenine-thymine base pair recognition: Formation of hydrogen bonds to the far-side adenine" @default.
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- W1976020349 doi "https://doi.org/10.1016/s0040-4039(99)00857-6" @default.
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