Matches in SemOpenAlex for { <https://semopenalex.org/work/W1976044510> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W1976044510 endingPage "126" @default.
- W1976044510 startingPage "120" @default.
- W1976044510 abstract "Extract: Rosette-forming cells (RFC) with more than 10 sheep red blood cells (SRBC's) per cell defined as morula-forming cells (MFC) were studied in human lymphoid organs and in the peripheral blood (PBL). MFC are most common in the thymus (more than 50%) and the frequency is much less in peripheral lymphoid tissues and in the blood (29.8% in those less than 5 years old; 14.9% in adults). There is very slight decrease in total RFC in PBL over age 5, but the changes in MFC are quite striking. Treatment with anti-human thymus antiserum (ATS) and with anti-human lymphoblastic antiserum (ATL) resulted in significant inhibition of total rosette and morula rosette formation. No inhibition was seen using normal brain antiserum, anti-IgM antiserum, or anti-L chain antiserum. In two patients with chronic lymphoeytic leukemia and in some cases of thymic deficiency the ratio of MFC to total RFC was unusually high. After culture with phytohemagglutinin (PHA) and conversion to blast forms or. after surface peturbation by papain or freeze-thaw treatment, MFC numbers were increased. Speculation: The reason that T cells bind SRBC without prior sensitization remains a mystery. Nevertheless, the reaction serves, as a reliable detector of a special class of immunologically competent Lymphocytes. Subpopulations within the two major classes of human lymphocytes (B and T cells) are now known. We speculate that an analysis of surface markers may help to detect these sub-classes. We suggest that the more primitive T cells may show the phenomenon of morula formation. It is postulated that the increase in MFC's might be due to the exposure of hidden sites or alteration of pre-existing surface receptors." @default.
- W1976044510 created "2016-06-24" @default.
- W1976044510 creator A5002424525 @default.
- W1976044510 creator A5018772705 @default.
- W1976044510 creator A5038285253 @default.
- W1976044510 creator A5049196354 @default.
- W1976044510 date "1976-02-01" @default.
- W1976044510 modified "2023-10-18" @default.
- W1976044510 title "Morula Forms of E Rosettes: Distribution, Specific Inhibition, and Enhancement" @default.
- W1976044510 cites W1520707423 @default.
- W1976044510 cites W1542231710 @default.
- W1976044510 cites W1583006402 @default.
- W1976044510 cites W1588496159 @default.
- W1976044510 cites W1653915792 @default.
- W1976044510 cites W1976283239 @default.
- W1976044510 cites W1977602326 @default.
- W1976044510 cites W1992742129 @default.
- W1976044510 cites W2011530504 @default.
- W1976044510 cites W2012652405 @default.
- W1976044510 cites W2013295182 @default.
- W1976044510 cites W2024976324 @default.
- W1976044510 cites W2032445942 @default.
- W1976044510 cites W2046507634 @default.
- W1976044510 cites W2050976516 @default.
- W1976044510 cites W20616761 @default.
- W1976044510 cites W2062721975 @default.
- W1976044510 cites W2073986350 @default.
- W1976044510 cites W2085897923 @default.
- W1976044510 cites W2109333116 @default.
- W1976044510 cites W2144212928 @default.
- W1976044510 cites W2339307525 @default.
- W1976044510 cites W2396039976 @default.
- W1976044510 cites W2409132082 @default.
- W1976044510 cites W2418447686 @default.
- W1976044510 cites W2992863929 @default.
- W1976044510 cites W66600094 @default.
- W1976044510 doi "https://doi.org/10.1203/00006450-197602000-00011" @default.
- W1976044510 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1082121" @default.
- W1976044510 hasPublicationYear "1976" @default.
- W1976044510 type Work @default.
- W1976044510 sameAs 1976044510 @default.
- W1976044510 citedByCount "4" @default.
- W1976044510 countsByYear W19760445102023 @default.
- W1976044510 crossrefType "journal-article" @default.
- W1976044510 hasAuthorship W1976044510A5002424525 @default.
- W1976044510 hasAuthorship W1976044510A5018772705 @default.
- W1976044510 hasAuthorship W1976044510A5038285253 @default.
- W1976044510 hasAuthorship W1976044510A5049196354 @default.
- W1976044510 hasBestOaLocation W19760445101 @default.
- W1976044510 hasConcept C153911025 @default.
- W1976044510 hasConcept C159654299 @default.
- W1976044510 hasConcept C181199279 @default.
- W1976044510 hasConcept C203014093 @default.
- W1976044510 hasConcept C2779832904 @default.
- W1976044510 hasConcept C2781414804 @default.
- W1976044510 hasConcept C3017413880 @default.
- W1976044510 hasConcept C3017910909 @default.
- W1976044510 hasConcept C55493867 @default.
- W1976044510 hasConcept C86803240 @default.
- W1976044510 hasConcept C91523082 @default.
- W1976044510 hasConceptScore W1976044510C153911025 @default.
- W1976044510 hasConceptScore W1976044510C159654299 @default.
- W1976044510 hasConceptScore W1976044510C181199279 @default.
- W1976044510 hasConceptScore W1976044510C203014093 @default.
- W1976044510 hasConceptScore W1976044510C2779832904 @default.
- W1976044510 hasConceptScore W1976044510C2781414804 @default.
- W1976044510 hasConceptScore W1976044510C3017413880 @default.
- W1976044510 hasConceptScore W1976044510C3017910909 @default.
- W1976044510 hasConceptScore W1976044510C55493867 @default.
- W1976044510 hasConceptScore W1976044510C86803240 @default.
- W1976044510 hasConceptScore W1976044510C91523082 @default.
- W1976044510 hasIssue "2" @default.
- W1976044510 hasLocation W19760445101 @default.
- W1976044510 hasLocation W19760445102 @default.
- W1976044510 hasOpenAccess W1976044510 @default.
- W1976044510 hasPrimaryLocation W19760445101 @default.
- W1976044510 hasRelatedWork W1973730979 @default.
- W1976044510 hasRelatedWork W1976044510 @default.
- W1976044510 hasRelatedWork W2009069814 @default.
- W1976044510 hasRelatedWork W2024814778 @default.
- W1976044510 hasRelatedWork W2355687456 @default.
- W1976044510 hasRelatedWork W2402149932 @default.
- W1976044510 hasRelatedWork W2410386300 @default.
- W1976044510 hasRelatedWork W2415773870 @default.
- W1976044510 hasRelatedWork W2429375503 @default.
- W1976044510 hasRelatedWork W2414965699 @default.
- W1976044510 hasVolume "10" @default.
- W1976044510 isParatext "false" @default.
- W1976044510 isRetracted "false" @default.
- W1976044510 magId "1976044510" @default.
- W1976044510 workType "article" @default.