Matches in SemOpenAlex for { <https://semopenalex.org/work/W1976057831> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W1976057831 endingPage "411" @default.
- W1976057831 startingPage "411" @default.
- W1976057831 abstract "Platelet-rich plasma (PRP) was prepared from cord blood collected in 1/12 volume 0.11 M sodium citrate and from adult blood in 1/9 volume citrate. PRP of newborn infants, mothers and normal adults was tested for aggregation with epinephrine, collagen and adenosine diphosphate (ADP). Total adenine nucleotide pools and adenine nucleotide metabolites were studied on 3H-adenine labelled PRP before and after exposure to collagen and epinephrine. Collagen and ADP-induced aggregation was similar in all 3 groups. Epinephrine, which induces 2-wave aggregation in adults, did not aggregate platelets of any infant, regardless of dose. Washed infant platelets, resuspended in group-compatible adult plasma, did not respond to epinephrine. Washed adult platelets, resuspended in compatible infant plasma showed 2-wave response. In unstimulated platelets of neonates, total adenine nucleotide pools were similar to those of adults or mothers. After collagen stimulation, neonatal platelets showed similar release of adenine nucleotides compared to the other 2 groups. Adenine nucleotide labelling patterns were similar in all groups. With epinephrine induction, platelets of neonates neither released adenine nucleotides into the plasma nor showed decreased nucleotides. There was no change in nucleotide labelling patterns. These studies suggest neonatal platelets have different epinephrine receptor sites from those of adults and there may be, in addition, an intrinsic structural membrane difference." @default.
- W1976057831 created "2016-06-24" @default.
- W1976057831 creator A5006857755 @default.
- W1976057831 creator A5009123179 @default.
- W1976057831 creator A5073476841 @default.
- W1976057831 creator A5083656883 @default.
- W1976057831 date "1974-04-01" @default.
- W1976057831 modified "2023-10-18" @default.
- W1976057831 title "THE PLATELET OF THE NEWBORN INFANT: AGGREGATION AND ADENINE NUCLEOTIDE RELEASE" @default.
- W1976057831 doi "https://doi.org/10.1203/00006450-197404000-00424" @default.
- W1976057831 hasPublicationYear "1974" @default.
- W1976057831 type Work @default.
- W1976057831 sameAs 1976057831 @default.
- W1976057831 citedByCount "1" @default.
- W1976057831 crossrefType "journal-article" @default.
- W1976057831 hasAuthorship W1976057831A5006857755 @default.
- W1976057831 hasAuthorship W1976057831A5009123179 @default.
- W1976057831 hasAuthorship W1976057831A5073476841 @default.
- W1976057831 hasAuthorship W1976057831A5083656883 @default.
- W1976057831 hasBestOaLocation W19760578311 @default.
- W1976057831 hasConcept C104317684 @default.
- W1976057831 hasConcept C126322002 @default.
- W1976057831 hasConcept C134018914 @default.
- W1976057831 hasConcept C185592680 @default.
- W1976057831 hasConcept C2775859304 @default.
- W1976057831 hasConcept C2776991684 @default.
- W1976057831 hasConcept C2777399203 @default.
- W1976057831 hasConcept C2780076745 @default.
- W1976057831 hasConcept C2780914630 @default.
- W1976057831 hasConcept C2993802102 @default.
- W1976057831 hasConcept C2994266630 @default.
- W1976057831 hasConcept C512185932 @default.
- W1976057831 hasConcept C55493867 @default.
- W1976057831 hasConcept C71924100 @default.
- W1976057831 hasConcept C89560881 @default.
- W1976057831 hasConceptScore W1976057831C104317684 @default.
- W1976057831 hasConceptScore W1976057831C126322002 @default.
- W1976057831 hasConceptScore W1976057831C134018914 @default.
- W1976057831 hasConceptScore W1976057831C185592680 @default.
- W1976057831 hasConceptScore W1976057831C2775859304 @default.
- W1976057831 hasConceptScore W1976057831C2776991684 @default.
- W1976057831 hasConceptScore W1976057831C2777399203 @default.
- W1976057831 hasConceptScore W1976057831C2780076745 @default.
- W1976057831 hasConceptScore W1976057831C2780914630 @default.
- W1976057831 hasConceptScore W1976057831C2993802102 @default.
- W1976057831 hasConceptScore W1976057831C2994266630 @default.
- W1976057831 hasConceptScore W1976057831C512185932 @default.
- W1976057831 hasConceptScore W1976057831C55493867 @default.
- W1976057831 hasConceptScore W1976057831C71924100 @default.
- W1976057831 hasConceptScore W1976057831C89560881 @default.
- W1976057831 hasIssue "4" @default.
- W1976057831 hasLocation W19760578311 @default.
- W1976057831 hasOpenAccess W1976057831 @default.
- W1976057831 hasPrimaryLocation W19760578311 @default.
- W1976057831 hasRelatedWork W1555297256 @default.
- W1976057831 hasRelatedWork W1967256782 @default.
- W1976057831 hasRelatedWork W1976057831 @default.
- W1976057831 hasRelatedWork W1979513115 @default.
- W1976057831 hasRelatedWork W2001940765 @default.
- W1976057831 hasRelatedWork W2186379476 @default.
- W1976057831 hasRelatedWork W2405499160 @default.
- W1976057831 hasRelatedWork W2412109466 @default.
- W1976057831 hasRelatedWork W2413095454 @default.
- W1976057831 hasRelatedWork W2415639617 @default.
- W1976057831 hasVolume "8" @default.
- W1976057831 isParatext "false" @default.
- W1976057831 isRetracted "false" @default.
- W1976057831 magId "1976057831" @default.
- W1976057831 workType "article" @default.