FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1976061249> ?p ?o ?g. }

• W1976061249 endingPage "1068" @default.
• W1976061249 startingPage "1067" @default.
• W1976061249 abstract "In the past 20 years, findings of epidemiological studies have substantially changed ideas about the incidence and phenotype of amyotrophic lateral sclerosis that were previously based on data from tertiary centres. In 2010, Logroscino and colleagues 1 Logroscino G Traynor BJ Hardiman O et al. Incidence of amyotrophic lateral sclerosis in Europe. J Neurol Neurosurg Psychiatry. 2010; 81: 385-390 Crossref PubMed Scopus (506) Google Scholar reported that like the two other major neurodegenerative diseases, Alzheimer's disease and Parkinson's disease, amyotrophic lateral sclerosis is age dependent, with peak incidence in people aged 70–80 years, and a flattening age-adjusted incidence curve thereafter. Phukan and colleagues 2 Phukan J Elamin M Bede P et al. The syndrome of cognitive impairment in amyotrophic lateral sclerosis: a population-based study. J Neurol Neurosurg Psychiatry. 2012; 83: 102-108 Crossref PubMed Scopus (466) Google Scholar reported a much broader disease phenotype than previously described and non-motor features (cognitive and behavioural) that affect prognosis. Uenal and colleagues 3 Uenal H Rosenbohm A Kufeldt J et al. Incidence and geographical variation of amyotrophic lateral sclerosis (ALS) in Southern Germany-completeness of the ALS registry Swabia. PLoS One. 2014; 9: e93932 Crossref PubMed Scopus (38) Google Scholar showed that incidence of amyotrophic lateral sclerosis is much higher than previously believed and was almost three per 100 000 people in Swabia, Germany. Logroscino and colleagues 4 Logroscino G Traynor BJ Hardiman O et al. Descriptive epidemiology of amyotrophic lateral sclerosis: new evidence and unsolved issues. J Neurol Neurosurg Psychiatry. 2008; 79: 6-11 Crossref PubMed Scopus (338) Google Scholar noted that incidence is expected to increase with the ageing of the general population, especially in women. However, even the most robust data have about 20% of cases missing, 3 Uenal H Rosenbohm A Kufeldt J et al. Incidence and geographical variation of amyotrophic lateral sclerosis (ALS) in Southern Germany-completeness of the ALS registry Swabia. PLoS One. 2014; 9: e93932 Crossref PubMed Scopus (38) Google Scholar and so far the contribution of observational studies to the understanding of the causes of amyotrophic lateral sclerosis has been limited. Genetics has identified several determinants, but the effect at the population level is small, even for mutations with high prevalence like C9orf72. 5 Al-Chalabi A Hardiman O The epidemiology of ALS: a conspiracy of genes, environment and time. Nat Rev Neurol. 2013; 9: 617-628 Crossref PubMed Scopus (462) Google Scholar Analysis of amyotrophic lateral sclerosis as a multistep process: a population-based modelling studyA linear relationship between the log incidence and log age of onset of amyotrophic lateral sclerosis is consistent with a multistage model of disease. The slope estimate suggests that amyotrophic lateral sclerosis is a six-step process. Identification of these steps could lead to preventive and therapeutic avenues. Full-Text PDF" @default.
• W1976061249 created "2016-06-24" @default.
• W1976061249 creator A5008484351 @default.
• W1976061249 creator A5047104019 @default.
• W1976061249 date "2014-11-01" @default.
• W1976061249 modified "2023-09-27" @default.
• W1976061249 title "Amyotrophic lateral sclerosis: new ideas from cancer" @default.
• W1976061249 cites W1503916499 @default.
• W1976061249 cites W1995963457 @default.
• W1976061249 cites W2001432662 @default.
• W1976061249 cites W2010652292 @default.
• W1976061249 cites W2050626075 @default.
• W1976061249 cites W2075967271 @default.
• W1976061249 cites W2098621159 @default.
• W1976061249 cites W2131461502 @default.
• W1976061249 cites W2157123931 @default.
• W1976061249 cites W2496321160 @default.
• W1976061249 doi "https://doi.org/10.1016/s1474-4422(14)70177-2" @default.
• W1976061249 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25300935" @default.
• W1976061249 hasPublicationYear "2014" @default.
• W1976061249 type Work @default.
• W1976061249 sameAs 1976061249 @default.
• W1976061249 citedByCount "3" @default.
• W1976061249 countsByYear W19760612492015 @default.
• W1976061249 countsByYear W19760612492018 @default.
• W1976061249 countsByYear W19760612492019 @default.
• W1976061249 crossrefType "journal-article" @default.
• W1976061249 hasAuthorship W1976061249A5008484351 @default.
• W1976061249 hasAuthorship W1976061249A5047104019 @default.
• W1976061249 hasConcept C107130276 @default.
• W1976061249 hasConcept C118552586 @default.
• W1976061249 hasConcept C120665830 @default.
• W1976061249 hasConcept C121332964 @default.
• W1976061249 hasConcept C142724271 @default.
• W1976061249 hasConcept C2779134260 @default.
• W1976061249 hasConcept C2780596555 @default.
• W1976061249 hasConcept C2908647359 @default.
• W1976061249 hasConcept C61511704 @default.
• W1976061249 hasConcept C71924100 @default.
• W1976061249 hasConcept C99454951 @default.
• W1976061249 hasConceptScore W1976061249C107130276 @default.
• W1976061249 hasConceptScore W1976061249C118552586 @default.
• W1976061249 hasConceptScore W1976061249C120665830 @default.
• W1976061249 hasConceptScore W1976061249C121332964 @default.
• W1976061249 hasConceptScore W1976061249C142724271 @default.
• W1976061249 hasConceptScore W1976061249C2779134260 @default.
• W1976061249 hasConceptScore W1976061249C2780596555 @default.
• W1976061249 hasConceptScore W1976061249C2908647359 @default.
• W1976061249 hasConceptScore W1976061249C61511704 @default.
• W1976061249 hasConceptScore W1976061249C71924100 @default.
• W1976061249 hasConceptScore W1976061249C99454951 @default.
• W1976061249 hasIssue "11" @default.
• W1976061249 hasLocation W19760612491 @default.
• W1976061249 hasLocation W19760612492 @default.
• W1976061249 hasOpenAccess W1976061249 @default.
• W1976061249 hasPrimaryLocation W19760612491 @default.
• W1976061249 hasRelatedWork W1539102636 @default.
• W1976061249 hasRelatedWork W1853158103 @default.
• W1976061249 hasRelatedWork W1970383787 @default.
• W1976061249 hasRelatedWork W1988420184 @default.
• W1976061249 hasRelatedWork W2275480158 @default.
• W1976061249 hasRelatedWork W2408945642 @default.
• W1976061249 hasRelatedWork W3095306390 @default.
• W1976061249 hasRelatedWork W33073900 @default.
• W1976061249 hasRelatedWork W4238089809 @default.
• W1976061249 hasRelatedWork W4241346791 @default.
• W1976061249 hasVolume "13" @default.
• W1976061249 isParatext "false" @default.
• W1976061249 isRetracted "false" @default.
• W1976061249 magId "1976061249" @default.
• W1976061249 workType "article" @default.