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• W1976083711 startingPage "490" @default.
• W1976083711 abstract "The effect of ionic strength on the generation of tension and upon the interfilament spacing in living intact and skinned single striated muscle fibers from the walking leg of crayfish (Orconectes) were determined by isometric contraction studies correlated with low-angle X-ray diffraction. Sarcomere lengths were determined by light diffraction. Tensions were induced in intact fibers by caffeine in the bathing medium and by ionophoretic microinjection of calcium. Tensions were induced in skinned fibers by a buffered calcium-EGTA solution. The interfilament spacing of intact and skinned fibers over the range of ionic strengths investigated were determined by X-ray diffraction and correlated with the physiological data. It is demonstrated that the ionic strength affects the tension-generating capacity of the muscle as it affects the chemo-mechanical transform of excitation-contraction coupling. It is further demonstrated that interfilament spacing changes encountered during shortening and with variation in the osmotic strength have no effect upon the tension-generating capacity of muscle." @default.
• W1976083711 created "2016-06-24" @default.
• W1976083711 creator A5023085484 @default.
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• W1976083711 date "1973-04-01" @default.
• W1976083711 modified "2023-10-15" @default.
• W1976083711 title "The Myofilament Lattice: Studies on Isolated Fibers" @default.
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• W1976083711 doi "https://doi.org/10.1085/jgp.61.4.490" @default.
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