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• W1976095228 startingPage "1375" @default.
• W1976095228 abstract "Nebulizers are a common device choice for use when developing a new drug product, but the range of nebulizer devices available can make it difficult to select the right device. Increasingly, companies are only able to promote a drug with the device that was used during the development program; therefore, choosing the best device at an early stage is important in order to achieve commercial success. Selecting a device that is inappropriate for the intended drug can result in poor drug delivery from the nebulizer to the patient, which would have obvious implications for the development program. As device performance varies, it is important to ensure that the most appropriate device is chosen for the intended drug to ensure optimal drug delivery to the patient population.In this review, the types of nebulizer devices available are highlighted, and the factors that should be taken into consideration when selecting the most appropriate device for a new drug are discussed. The review is broadly divided into drug, device, patient and trial characteristics.Efficient nebulizer devices that combine electronic monitoring capabilities as a form of telehealth are likely to provide superior drug delivery to patients and accurate clinical trial data. Their use in adaptive clinical trials may help to vastly reduce the time and costs associated with achieving drug approval." @default.
• W1976095228 created "2016-06-24" @default.
• W1976095228 creator A5002097416 @default.
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• W1976095228 creator A5059202125 @default.
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• W1976095228 date "2015-03-10" @default.
• W1976095228 modified "2023-09-27" @default.
• W1976095228 title "Factors to consider when selecting a nebulizer for a new inhaled drug product development program" @default.
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• W1976095228 doi "https://doi.org/10.1517/17425247.2015.1014339" @default.
• W1976095228 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25758911" @default.
• W1976095228 hasPublicationYear "2015" @default.
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