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• W1976096573 abstract "Two series of novel diaryl ureas have been designed and synthesized, with their in vitro antitumor effect screened on human non-small cell lung cancer (NSCLC) cell line A549 and human breast cancer cell line MDA-MB-231. Some target compounds demonstrated significant inhibitory activities against both cell lines. Compared to contrast drug Sorafenib, 1b, 1d, 1f, 1i were found to demonstrate more potent antitumor activities. The structures of all the newly synthesized compounds were determined by 1H, 13C NMR, MS, IR and elementary analysis." @default.
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• W1976096573 date "2010-06-01" @default.
• W1976096573 modified "2023-10-16" @default.
• W1976096573 title "Design, synthesis, and in vitro antitumor evaluation of novel diaryl ureas derivatives" @default.
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• W1976096573 doi "https://doi.org/10.1016/j.ejmech.2010.02.005" @default.
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