Matches in SemOpenAlex for { <https://semopenalex.org/work/W1976106457> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W1976106457 endingPage "1268" @default.
- W1976106457 startingPage "1263" @default.
- W1976106457 abstract "Assessment of risk and appropriate management of patients with acute pulmonary embolism (PE) remains a challenge. Cardiac troponins I (cTnI) and T (cTnT) are reliable indicators of myocardial injury and may be associated with right ventricular dysfunction in PE.The present prospective study included 106 consecutive patients with confirmed acute PE. cTnI was elevated (> or =0.07 ng/mL) in 43 patients (41%), and cTnT (> or =0.04 ng/mL) was elevated in 39 (37%). Elevation of cTnI or cTnT was significantly associated with echocardiographically detected right ventricular dysfunction (P=0.001 and P<0.05, respectively). Moreover, a significant correlation was found between elevation of cTnI or cTnT and the two major end points overall mortality and complicated in-hospital course. The negative predictive value of cardiac troponins for major clinical events was 92% to 93%. Importantly, there was obvious escalation of in-hospital mortality, the rate of complications, and the incidence of recurrent PE, when patients with high troponin concentrations (cTnI >1.5; cTnT >0.1 ng/mL) were compared with those with only moderately elevated levels (cTnI, 0.07 to 1.5; cTnT, 0.04 to 0.1 ng/mL). Logistic regression analysis confirmed that the mortality risk (OR) was significantly elevated only in patients with high cTnI (P=0.019) or cTnT (P=0.038) levels. Furthermore, the risk of a complicated in-hospital course was almost 5 times higher (15.47 versus 3.16) in the high-cTnI group compared with patients with moderate cTnI elevation.Our results indicate that cTnI and cTnT may be a novel, particularly useful tool for optimizing the management strategy in patients with acute PE." @default.
- W1976106457 created "2016-06-24" @default.
- W1976106457 creator A5008206072 @default.
- W1976106457 creator A5011835640 @default.
- W1976106457 creator A5016970340 @default.
- W1976106457 creator A5023431874 @default.
- W1976106457 creator A5042248757 @default.
- W1976106457 creator A5054454843 @default.
- W1976106457 creator A5064318838 @default.
- W1976106457 date "2002-09-03" @default.
- W1976106457 modified "2023-09-25" @default.
- W1976106457 title "Importance of Cardiac Troponins I and T in Risk Stratification of Patients With Acute Pulmonary Embolism" @default.
- W1976106457 cites W1996942864 @default.
- W1976106457 cites W2002122302 @default.
- W1976106457 cites W2020900565 @default.
- W1976106457 cites W2057440193 @default.
- W1976106457 cites W2069080267 @default.
- W1976106457 cites W2102535207 @default.
- W1976106457 cites W2141100139 @default.
- W1976106457 cites W2144242797 @default.
- W1976106457 cites W2148653105 @default.
- W1976106457 cites W2316248832 @default.
- W1976106457 cites W2316599968 @default.
- W1976106457 cites W2340367584 @default.
- W1976106457 doi "https://doi.org/10.1161/01.cir.0000028422.51668.a2" @default.
- W1976106457 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12208803" @default.
- W1976106457 hasPublicationYear "2002" @default.
- W1976106457 type Work @default.
- W1976106457 sameAs 1976106457 @default.
- W1976106457 citedByCount "417" @default.
- W1976106457 countsByYear W19761064572012 @default.
- W1976106457 countsByYear W19761064572013 @default.
- W1976106457 countsByYear W19761064572014 @default.
- W1976106457 countsByYear W19761064572015 @default.
- W1976106457 countsByYear W19761064572016 @default.
- W1976106457 countsByYear W19761064572017 @default.
- W1976106457 countsByYear W19761064572018 @default.
- W1976106457 countsByYear W19761064572019 @default.
- W1976106457 countsByYear W19761064572020 @default.
- W1976106457 countsByYear W19761064572021 @default.
- W1976106457 countsByYear W19761064572022 @default.
- W1976106457 countsByYear W19761064572023 @default.
- W1976106457 crossrefType "journal-article" @default.
- W1976106457 hasAuthorship W1976106457A5008206072 @default.
- W1976106457 hasAuthorship W1976106457A5011835640 @default.
- W1976106457 hasAuthorship W1976106457A5016970340 @default.
- W1976106457 hasAuthorship W1976106457A5023431874 @default.
- W1976106457 hasAuthorship W1976106457A5042248757 @default.
- W1976106457 hasAuthorship W1976106457A5054454843 @default.
- W1976106457 hasAuthorship W1976106457A5064318838 @default.
- W1976106457 hasBestOaLocation W19761064571 @default.
- W1976106457 hasConcept C115725540 @default.
- W1976106457 hasConcept C120665830 @default.
- W1976106457 hasConcept C121332964 @default.
- W1976106457 hasConcept C126322002 @default.
- W1976106457 hasConcept C164705383 @default.
- W1976106457 hasConcept C2776265017 @default.
- W1976106457 hasConcept C36036425 @default.
- W1976106457 hasConcept C500558357 @default.
- W1976106457 hasConcept C61511704 @default.
- W1976106457 hasConcept C71924100 @default.
- W1976106457 hasConcept C8880881 @default.
- W1976106457 hasConceptScore W1976106457C115725540 @default.
- W1976106457 hasConceptScore W1976106457C120665830 @default.
- W1976106457 hasConceptScore W1976106457C121332964 @default.
- W1976106457 hasConceptScore W1976106457C126322002 @default.
- W1976106457 hasConceptScore W1976106457C164705383 @default.
- W1976106457 hasConceptScore W1976106457C2776265017 @default.
- W1976106457 hasConceptScore W1976106457C36036425 @default.
- W1976106457 hasConceptScore W1976106457C500558357 @default.
- W1976106457 hasConceptScore W1976106457C61511704 @default.
- W1976106457 hasConceptScore W1976106457C71924100 @default.
- W1976106457 hasConceptScore W1976106457C8880881 @default.
- W1976106457 hasIssue "10" @default.
- W1976106457 hasLocation W19761064571 @default.
- W1976106457 hasLocation W19761064572 @default.
- W1976106457 hasOpenAccess W1976106457 @default.
- W1976106457 hasPrimaryLocation W19761064571 @default.
- W1976106457 hasRelatedWork W1855417670 @default.
- W1976106457 hasRelatedWork W1986570242 @default.
- W1976106457 hasRelatedWork W2004656475 @default.
- W1976106457 hasRelatedWork W2041217399 @default.
- W1976106457 hasRelatedWork W2114115913 @default.
- W1976106457 hasRelatedWork W2142108969 @default.
- W1976106457 hasRelatedWork W2334709023 @default.
- W1976106457 hasRelatedWork W2402927453 @default.
- W1976106457 hasRelatedWork W2754268774 @default.
- W1976106457 hasRelatedWork W4281782385 @default.
- W1976106457 hasVolume "106" @default.
- W1976106457 isParatext "false" @default.
- W1976106457 isRetracted "false" @default.
- W1976106457 magId "1976106457" @default.
- W1976106457 workType "article" @default.