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- W1976115828 endingPage "1071" @default.
- W1976115828 startingPage "1066" @default.
- W1976115828 abstract "Nocardiopsis sp. K-290 was found to produce novel metabolites, designated K-252b, c and d, which were structurally related to K-252a. These compounds were isolated from the culture broth and the physico-chemical and biochemical properties were examined. The compounds strongly inhibited protein kinase C. IC50 values (the concentrations causing 50% inhibition) for the effects of K-252b, c and d on the rat brain enzyme were 38.3, 214, and 337 nM, respectively." @default.
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- W1976115828 date "1986-01-01" @default.
- W1976115828 modified "2023-10-11" @default.
- W1976115828 title "K-252b, c and d, potent inhibitors of protein kinase C from microbial origin." @default.
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- W1976115828 doi "https://doi.org/10.7164/antibiotics.39.1066" @default.
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