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- W1976140432 abstract "Wide publicity has been given in America during the past year to Schick's discovery of the skin reaction to diphtheria toxin. This reaction is of interest in the treatment of exposed individuals because of its bearing on the practice of passive immunization. Schick<sup>1</sup>in 1913 published his conclusions and results, which I summarize as follows: Diphtheritic children before a serum injection possess no protection bodies against the toxin of diphtheria. The prophylactic use of antitoxic serum supplies this lack. Many individuals without ever having shown symptoms of a diphtheria infection, already possess antibodies: in the new-born, 80 per cent.; older children, up to 50 and 60 per cent., and adults, up to 90 per cent. Children 2 to 5 years of age gave the highest percentage of positive reactions. For a great number of persons, therefore, the prophylactic injection could be abandoned. Schick finally adopted 0.1 c.c. of a" @default.
- W1976140432 created "2016-06-24" @default.
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- W1976140432 date "1915-08-14" @default.
- W1976140432 modified "2023-09-25" @default.
- W1976140432 title "THE RECENT METHODS OF TREATING DIPHTHERIA" @default.
- W1976140432 doi "https://doi.org/10.1001/jama.1915.02580070019006" @default.
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