FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1976143235> ?p ?o ?g. }

• W1976143235 endingPage "249" @default.
• W1976143235 startingPage "240" @default.
• W1976143235 abstract "Insulin-like growth factor 2 (IGF2) is a protein hormone known to regulate cell proliferation, growth, migration, differentiation and survival. The gene is parentally imprinted in the sense that transcripts are almost exclusively derived from the paternal allele. Loss of imprinting of the IGF2 gene is a recurrent observation in growth disorders that combine overgrowth with a variety of malignant tumours. Moreover, IGF2 has been proposed to play a role in the development of a variety of seemingly unrelated cancers that play an important role in geriatric medicine, e.g., breast cancer, colon cancer and lung cancer. Finally, IGF2 has been implicated in cardiovascular disease, since, for example, IGF2 has been shown to influence the size of atherosclerotic lesions.To summarize current knowledge about IGF2, its interactions with binding proteins and receptors and connections with key diseases.The contents of this paper were based on reviews of existing literature within the field.There is a substantial amount of research linking IGF2 to growth disorders, cancer and to a much lesser degree cardiovascular disease. Some of the studies on IGF2 and tumour growth have yielded conflicting results, for instance regarding its effect on apoptosis.Today, our knowledge on how IGF2 is composed and interacts with receptors has come a long way. However, there is comparatively little information on how IGF2 affects tumour growth and cardiovascular diseases such as atherosclerosis. Thus, further research will be needed to elucidate the impact of IGF2 on key diseases." @default.
• W1976143235 created "2016-06-24" @default.
• W1976143235 creator A5006870503 @default.
• W1976143235 creator A5016399556 @default.
• W1976143235 creator A5030023470 @default.
• W1976143235 creator A5038866861 @default.
• W1976143235 date "2012-12-20" @default.
• W1976143235 modified "2023-10-12" @default.
• W1976143235 title "Insulin-Like Growth Factor 2 in Development and Disease: A Mini-Review" @default.
• W1976143235 cites W1515707502 @default.
• W1976143235 cites W1835811038 @default.
• W1976143235 cites W1972454974 @default.
• W1976143235 cites W1987973079 @default.
• W1976143235 cites W1988904267 @default.
• W1976143235 cites W1994242945 @default.
• W1976143235 cites W1997146974 @default.
• W1976143235 cites W2009344472 @default.
• W1976143235 cites W2014418366 @default.
• W1976143235 cites W2014798423 @default.
• W1976143235 cites W2048852715 @default.
• W1976143235 cites W2051839343 @default.
• W1976143235 cites W2052334424 @default.
• W1976143235 cites W2074647644 @default.
• W1976143235 cites W2080743352 @default.
• W1976143235 cites W2083354235 @default.
• W1976143235 cites W2089419766 @default.
• W1976143235 cites W2090928430 @default.
• W1976143235 cites W2100298565 @default.
• W1976143235 cites W2110334888 @default.
• W1976143235 cites W2125853470 @default.
• W1976143235 cites W2132313422 @default.
• W1976143235 cites W2141751576 @default.
• W1976143235 cites W2143145174 @default.
• W1976143235 cites W2151646894 @default.
• W1976143235 cites W2162601546 @default.
• W1976143235 cites W2163035954 @default.
• W1976143235 cites W2166250242 @default.
• W1976143235 cites W4211064310 @default.
• W1976143235 cites W4254760279 @default.
• W1976143235 doi "https://doi.org/10.1159/000343995" @default.
• W1976143235 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23257688" @default.
• W1976143235 hasPublicationYear "2012" @default.
• W1976143235 type Work @default.
• W1976143235 sameAs 1976143235 @default.
• W1976143235 citedByCount "184" @default.
• W1976143235 countsByYear W19761432352013 @default.
• W1976143235 countsByYear W19761432352014 @default.
• W1976143235 countsByYear W19761432352015 @default.
• W1976143235 countsByYear W19761432352016 @default.
• W1976143235 countsByYear W19761432352017 @default.
• W1976143235 countsByYear W19761432352018 @default.
• W1976143235 countsByYear W19761432352019 @default.
• W1976143235 countsByYear W19761432352020 @default.
• W1976143235 countsByYear W19761432352021 @default.
• W1976143235 countsByYear W19761432352022 @default.
• W1976143235 countsByYear W19761432352023 @default.
• W1976143235 crossrefType "journal-article" @default.
• W1976143235 hasAuthorship W1976143235A5006870503 @default.
• W1976143235 hasAuthorship W1976143235A5016399556 @default.
• W1976143235 hasAuthorship W1976143235A5030023470 @default.
• W1976143235 hasAuthorship W1976143235A5038866861 @default.
• W1976143235 hasBestOaLocation W19761432351 @default.
• W1976143235 hasConcept C104317684 @default.
• W1976143235 hasConcept C121608353 @default.
• W1976143235 hasConcept C126322002 @default.
• W1976143235 hasConcept C144174609 @default.
• W1976143235 hasConcept C150194340 @default.
• W1976143235 hasConcept C170493617 @default.
• W1976143235 hasConcept C180754005 @default.
• W1976143235 hasConcept C190727270 @default.
• W1976143235 hasConcept C201492766 @default.
• W1976143235 hasConcept C203014093 @default.
• W1976143235 hasConcept C21936154 @default.
• W1976143235 hasConcept C2775960820 @default.
• W1976143235 hasConcept C2779069268 @default.
• W1976143235 hasConcept C2779134260 @default.
• W1976143235 hasConcept C2780689927 @default.
• W1976143235 hasConcept C502942594 @default.
• W1976143235 hasConcept C54355233 @default.
• W1976143235 hasConcept C60644358 @default.
• W1976143235 hasConcept C71924100 @default.
• W1976143235 hasConcept C86803240 @default.
• W1976143235 hasConcept C94715292 @default.
• W1976143235 hasConceptScore W1976143235C104317684 @default.
• W1976143235 hasConceptScore W1976143235C121608353 @default.
• W1976143235 hasConceptScore W1976143235C126322002 @default.
• W1976143235 hasConceptScore W1976143235C144174609 @default.
• W1976143235 hasConceptScore W1976143235C150194340 @default.
• W1976143235 hasConceptScore W1976143235C170493617 @default.
• W1976143235 hasConceptScore W1976143235C180754005 @default.
• W1976143235 hasConceptScore W1976143235C190727270 @default.
• W1976143235 hasConceptScore W1976143235C201492766 @default.
• W1976143235 hasConceptScore W1976143235C203014093 @default.
• W1976143235 hasConceptScore W1976143235C21936154 @default.
• W1976143235 hasConceptScore W1976143235C2775960820 @default.
• W1976143235 hasConceptScore W1976143235C2779069268 @default.
• W1976143235 hasConceptScore W1976143235C2779134260 @default.
• W1976143235 hasConceptScore W1976143235C2780689927 @default.

• next