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- W1976147989 abstract "Autologous blood transfusion has been avoided in cancer surgery because of the metastatic potential of reinfused tumour cells.This study evaluated the efficacy of a blood transfusion filter in removing tumour cells from blood. Whole human blood was admixed with two different malignant cell lines (breast cancer PM1 and MCF7). The blood was filtered through a RC400TE leucocyte depletion filter. Unfiltered blood was used as a control. Detection of malignant cells was performed with immunomagnetic beads and clonogenic assays.No viable tumour cells were found after filtration with the leucocyte depletion filter.These findings suggest that the use of a leucocyte filter after intra-operative blood salvage may make autotransfusion safe even in tumour surgery." @default.
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- W1976147989 date "1996-01-01" @default.
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- W1976147989 title "Leucocyte depletion filter removes cancer cells in human blood" @default.
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- W1976147989 doi "https://doi.org/10.1111/j.1399-6576.1996.tb04397.x" @default.
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