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- W1976162562 abstract "PROBLEM: The aim of this study was to contribute to the study of the pathogenesis and the treatment of recurrent spontaneous abortion (RSA) associated with immune alterations. METHOD OF STUDY: This is a prospective clinical trial with 11 patients with RSA associated with allo- and autoimmunity not receiving lymphocyte immunizations but only heparin and aspirin preconceptionally and through pregnancy. A concurrent group of 8 patients receiving a complete therapy (lymphocyte immunizations, heparin, and aspirin) but not receiving heparin and aspirin preconceptionally is also included in this report. RESULTS: The rate of pregnancy success in these patients was 90.9% (10/11), and the rate of success of the concurrent group was 75.0% (6/8). CONCLUSIONS: The results are in agreement with the working hypothesis regarding the possible final common mechanism in the pathogenesis of abortion associated with allo- and autoimmunity. The “single” therapy with heparin and aspirin was effective, less costly, and logistically simpler to provide than a complete therapy including lymphocyte immunizations." @default.
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- W1976162562 date "1999-04-01" @default.
- W1976162562 modified "2023-10-16" @default.
- W1976162562 title "Heparin Plus Aspirin as a “Single” Therapy for Recurrent Spontaneous Abortion Associated with both Allo- and Autoimmunity" @default.
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- W1976162562 doi "https://doi.org/10.1111/j.1600-0897.1999.tb00438.x" @default.
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